U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [ Danio rerio (zebrafish) ]

Gene ID: 561771, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
acap1provided by ZNC
Official Full Name
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-070112-1242
See related
Ensembl:ENSDARG00000056346 AllianceGenome:ZFIN:ZDB-GENE-070112-1242
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Cnt-b1; centb1; zgc:153917
Summary
Predicted to enable GTPase activator activity and metal ion binding activity. Is expressed in intestine. Orthologous to human ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See acap1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
24
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (20058857..20103332, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (19806889..19851364, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene BCL6B transcription repressor Neighboring gene solute carrier family 16 member 13 Neighboring gene ArfGAP with FG repeats 2 Neighboring gene si:ch73-335l21.1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish. Oehlers SH, et al. Dis Model Mech, 2011 Nov. PMID 21729873, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080579.1 → NP_001074048.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

    See identical proteins and their annotated locations for NP_001074048.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129036
    UniProtKB/TrEMBL
    A0A8M1NBL4, A1L1F5
    Related
    ENSDARP00000052901.6, ENSDART00000052902.9
    Conserved Domains (7) summary
    cd00204
    Location:583 → 709
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:269 → 365
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:269 → 361
    PH; PH domain
    pfam01412
    Location:398 → 516
    ArfGap; Putative GTPase activating protein for Arf
    pfam12796
    Location:593 → 687
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:623 → 654
    ANK; ANK repeat [structural motif]
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    20058857..20103332 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394684.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    201812..246233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.