pigl phosphatidylinositol glycan anchor biosynthesis, class L [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: piglprovided by ZNC
Official Full Name: phosphatidylinositol glycan anchor biosynthesis, class Lprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050506-60
See related: Ensembl:ENSDARG00000067752 AllianceGenome:ZFIN:ZDB-GENE-050506-60
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:6902701; si:ch211-202a12.6
Summary: Predicted to enable N-acetylglucosaminylphosphatidylinositol deacetylase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in CHIME syndrome. Orthologous to human PIGL (phosphatidylinositol glycan anchor biosynthesis class L). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (41996897..42054070)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (41396744..41453917)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables N-acetylglucosaminylphosphatidylinositol deacetylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acetylglucosaminylphosphatidylinositol deacetylase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in GPI anchor biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

NP_001243584.1

EC 3.5.1.89

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001256655.1 → NP_001243584.1 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

Status: PROVISIONAL

Source sequence(s)

BC142909

UniProtKB/TrEMBL

A0A8M1P3K2, A5PLH9

Related

ENSDARP00000088351.3, ENSDART00000097580.5

Conserved Domains (1) summary

pfam02585
Location:74 → 191

PIG-L; GlcNAc-PI de-N-acetylase