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dazap1 DAZ associated protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 561459, updated on 17-Aug-2024

Summary

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Official Symbol
dazap1provided by ZNC
Official Full Name
DAZ associated protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-070212-1
See related
Ensembl:ENSDARG00000070846 AllianceGenome:ZFIN:ZDB-GENE-070212-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable mRNA 3'-UTR binding activity; poly(G) binding activity; and poly(U) RNA binding activity. Predicted to be involved in positive regulation of mRNA splicing, via spliceosome and spermatogenesis. Is expressed in Purkinje cell. Orthologous to human DAZAP1 (DAZ associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See dazap1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (5880529..5923741)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (5883269..5926486)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase core subunit S7 Neighboring gene guanidinoacetate N-methyltransferase Neighboring gene ribosomal protein S15 Neighboring gene abhydrolase domain containing 8b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Amyloid-like Self-Assembly of a Cellular Compartment. Boke E, et al. Cell, 2016 Jul 28. PMID 27471966, Free PMC Article
  2. Sox9-related signaling controls zebrafish juvenile ovary-testis transformation. Sun D, et al. Cell Death Dis, 2013 Nov 21. PMID 24263104, Free PMC Article
  3. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. Takeuchi M, et al. J Comp Neurol, 2017 May 1. PMID 27615194
  4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables poly(G) binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spermatogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DAZ-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001173504.1 → NP_001166975.1  DAZ-associated protein 1

    Status: VALIDATED

    Source sequence(s)
    BC114331, BX255969
    UniProtKB/TrEMBL
    A0A8M1NT42, Q29R83
    Related
    ENSDARP00000111358.1, ENSDART00000129663.3
    Conserved Domains (2) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    5880529..5923741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479633.1 → XP_021335308.1  DAZ-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q795, Q29R83
    Conserved Domains (3) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cl28087
    Location:220 → 430
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]

  2. XM_021479635.1 → XP_021335310.1  DAZ-associated protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8M9QLN5, Q29R83
    Conserved Domains (3) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cl28087
    Location:195 → 359
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]

  3. XM_005155696.4 → XP_005155753.1  DAZ-associated protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A0R4IAW9, A0A8M2B2G3, Q29R83
    Related
    ENSDARP00000130727.3, ENSDART00000160909.3
    Conserved Domains (2) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins

  4. XM_021479634.1 → XP_021335309.1  DAZ-associated protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M9QD50, Q29R83
    Conserved Domains (3) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cl28087
    Location:220 → 429
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]

  5. XM_021479636.1 → XP_021335311.1  DAZ-associated protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8M9QHQ2, Q29R83
    Conserved Domains (3) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cl28087
    Location:220 → 406
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]

  6. XM_009305803.3 → XP_009304078.1  DAZ-associated protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8M3B6Q5, Q29R83
    Conserved Domains (2) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins

  7. XM_017358237.2 → XP_017213726.1  DAZ-associated protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8M6Z386, Q29R83

  8. XM_005155697.4 → XP_005155754.1  DAZ-associated protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8M2B1W2, Q29R83
    Related
    ENSDARP00000109996.1, ENSDART00000130768.3
    Conserved Domains (2) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins

  9. XM_005155698.4 → XP_005155755.1  DAZ-associated protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A8M2B1T5, Q29R83
    Conserved Domains (2) summary
    cd12327
    Location:127 → 202
    RRM2_DAZAP1; RNA recognition motif 2 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins
    cd12574
    Location:24 → 105
    RRM1_DAZAP1; RNA recognition motif 1 in Deleted in azoospermia-associated protein 1 (DAZAP1) and similar proteins

  10. XM_021479637.1 → XP_021335312.1  DAZ-associated protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8M9PUZ2
    Conserved Domains (1) summary
    cl28087
    Location:35 → 245
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394801.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    75906..119011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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