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b3gnt3.4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tandem duplicate 4 [ Danio rerio (zebrafish) ]

Gene ID: 561172, updated on 12-Sep-2024

Summary

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Official Symbol
b3gnt3.4provided by ZNC
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tandem duplicate 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8875
See related
Ensembl:ENSDARG00000058100 AllianceGenome:ZFIN:ZDB-GENE-030131-8875
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
b3gnt3; wu:fk30b12; zgc:171538
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. Is expressed in blood. Orthologous to several human genes including B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See b3gnt3.4 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (13630058..13642590, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (13592350..13603330, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene si:ch211-126g16.8 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tendem duplicate 2 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tandem duplicate 3 Neighboring gene very low-density lipoprotein receptor Neighboring gene novel protein similar to vertebrate pim oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification of vasculature-specific genes by microarray analysis of Etsrp/Etv2 overexpressing zebrafish embryos. Wong KS, et al. Dev Dyn, 2009 Jul. PMID 19504456
  2. Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development. Cannon JE, et al. Mech Dev, 2013 Feb. PMID 23072875, Free PMC Article
  3. Evolution of JAK-STAT pathway components: mechanisms and role in immune system development. Liongue C, et al. PLoS One, 2012. PMID 22412924, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC171538

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in poly-N-acetyllactosamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4
Names
beta-3-galactosyltransferase-like
NP_001103580.1
XP_005166911.1
XP_005166913.1
XP_009302084.1
XP_068079082.1
XP_068079083.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110110.2 → NP_001103580.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4

    See identical proteins and their annotated locations for NP_001103580.1

    Status: VALIDATED

    Source sequence(s)
    CR786572
    UniProtKB/TrEMBL
    A0A8M1NG76, A8KB44
    Related
    ENSDARP00000075319.3, ENSDART00000080875.4
    Conserved Domains (1) summary
    cl21608
    Location:126 → 321
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    13630058..13642590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068222982.1 → XP_068079083.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

  2. XM_005166854.5 → XP_005166911.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

    See identical proteins and their annotated locations for XP_005166911.1

    UniProtKB/TrEMBL
    A0A8M1NG76, A8KB44
    Conserved Domains (1) summary
    cl21608
    Location:126 → 321
    Galactosyl_T; Galactosyltransferase

  3. XM_009303809.4 → XP_009302084.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

    See identical proteins and their annotated locations for XP_009302084.1

    UniProtKB/TrEMBL
    A0A8M1NG76, A8KB44
    Conserved Domains (1) summary
    cl21608
    Location:126 → 321
    Galactosyl_T; Galactosyltransferase

  4. XM_005166856.5 → XP_005166913.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

    See identical proteins and their annotated locations for XP_005166913.1

    UniProtKB/TrEMBL
    A0A8M1NG76, A8KB44
    Conserved Domains (1) summary
    cl21608
    Location:126 → 321
    Galactosyl_T; Galactosyltransferase

  5. XM_068222981.1 → XP_068079082.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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