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epn2 epsin 2 [ Danio rerio (zebrafish) ]

Gene ID: 560542, updated on 2-Nov-2024

Summary

Official Symbol
epn2provided by ZNC
Official Full Name
epsin 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-071212-1
See related
Ensembl:ENSDARG00000008377 AllianceGenome:ZFIN:ZDB-GENE-071212-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb51h11; fs38h01; wu:fb51h11; wu:fs38h01
Summary
Predicted to enable clathrin binding activity and phospholipid binding activity. Predicted to be involved in endocytosis. Predicted to be located in cytoplasm. Predicted to be part of clathrin vesicle coat. Predicted to be active in endosome and plasma membrane. Orthologous to human EPN2 (epsin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See epn2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (39656524..39690216)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (39514631..39548360)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83 member Ga Neighboring gene GRB2 related adaptor protein a Neighboring gene B9 protein domain 1 Neighboring gene calcium channel, voltage-dependent, T type, alpha 1H subunit a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of clathrin vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    39656524..39690216
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_681373.9XP_686465.3  epsin-2 isoform X1

    UniProtKB/TrEMBL
    A0A8N7TAM9, E7EYW2
    Related
    ENSDARP00000128983.1, ENSDART00000156038.2
    Conserved Domains (1) summary
    cd03571
    Location:19141
    ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
  2. XM_009299683.4XP_009297958.1  epsin-2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3B8G3
    Related
    ENSDARP00000156149.1, ENSDART00000184573.1
    Conserved Domains (1) summary
    cd03571
    Location:19141
    ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...