cdaa cytidine deaminase a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cdaaprovided by ZNC
Official Full Name: cytidine deaminase aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-170609-2
See related: Ensembl:ENSDARG00000111188 AllianceGenome:ZFIN:ZDB-GENE-170609-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable cytidine deaminase activity and zinc ion binding activity. Predicted to be involved in cytidine deamination. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human CDA (cytidine deaminase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (37458602..37466326)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (37355932..37361913)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables cytidine deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables cytidine deaminase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cytidine deamination	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cytidine deamination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytidine deaminase a

NP_001338644.1

EC 3.5.4.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001351715.1 → NP_001338644.1 cytidine deaminase a

Status: PROVISIONAL

Source sequence(s)

AL954146, CD605377, EH452518

UniProtKB/TrEMBL

A0A8M1P5S0

Related

ENSDARP00000156561.1, ENSDART00000181686.1

Conserved Domains (1) summary

TIGR01354
Location:9 → 133

cyt_deam_tetra; cytidine deaminase, homotetrameric