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mpnd MPN domain containing [ Danio rerio (zebrafish) ]

Gene ID: 559169, updated on 12-Sep-2024

Summary

Official Symbol
mpndprovided by ZNC
Official Full Name
MPN domain containingprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-1162
See related
Ensembl:ENSDARG00000061989 AllianceGenome:ZFIN:ZDB-GENE-060929-1162
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj55b03; wu:fj55b03; zgc:153076
Summary
Predicted to enable histone binding activity; peptidase activity; and transcription coactivator activity. Predicted to be involved in chromatin remodeling and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within proteolysis. Orthologous to human MPND (MPN domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See mpnd in Genome Data Viewer
Location:
chromosome: 8
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (18830932..18840694)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (18800515..18810277)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496295 Neighboring gene uncharacterized LOC137496296 Neighboring gene SH3-domain GRB2-like 1b Neighboring gene RAR-related orphan receptor C a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC153076

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in double-strand break repair IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of BRCA1-A complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of BRISC complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
MPN domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076565.1NP_001070033.1  MPN domain-containing protein

    See identical proteins and their annotated locations for NP_001070033.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124239
    UniProtKB/Swiss-Prot
    Q08CH3
    Related
    ENSDARP00000083512.4, ENSDART00000089079.6
    Conserved Domains (1) summary
    cd08067
    Location:223407
    MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    18830932..18840694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)