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psd2 pleckstrin and Sec7 domain containing 2 [ Danio rerio (zebrafish) ]

Gene ID: 557199, updated on 2-Nov-2024

Summary

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Official Symbol
psd2provided by ZNC
Official Full Name
pleckstrin and Sec7 domain containing 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3033
See related
Ensembl:ENSDARG00000063036 AllianceGenome:ZFIN:ZDB-GENE-030131-3033
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc25d04; wu:fc25d04; si: dkey-29k15.1
Summary
Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Acts upstream of or within heart development; larval locomotory behavior; and somite development. Predicted to be located in ruffle membrane. Orthologous to human PSD2 (pleckstrin and Sec7 domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See psd2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (8128041..8249333)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (7821772..7943219)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene CXXC finger protein 5b Neighboring gene uncharacterized LOC137487563 Neighboring gene zgc:92242 Neighboring gene purine-rich element binding protein Ab Neighboring gene neuregulin 2b Neighboring gene nucleosome assembly protein 1-like 1-A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Large-scale discovery of novel genetic causes of developmental disorders. Deciphering Developmental Disorders Study. Nature, 2015 Mar 12. PMID 25533962, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within larval locomotory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within somite development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in ruffle membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
PH and SEC7 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    8128041..8249333
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213301.1 → XP_068069402.1  PH and SEC7 domain-containing protein 2 isoform X2

    Related
    ENSDARP00000130218.1, ENSDART00000169091.2

  2. XM_068213300.1 → XP_068069401.1  PH and SEC7 domain-containing protein 2 isoform X1

  3. XM_068213302.1 → XP_068069403.1  PH and SEC7 domain-containing protein 2 isoform X3

Nucleotide Protein
Heading Accession and Version

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