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strip2 striatin interacting protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 556392, updated on 12-Sep-2024

Summary

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Official Symbol
strip2provided by ZNC
Official Full Name
striatin interacting protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-120328-1
See related
Ensembl:ENSDARG00000059003 AllianceGenome:ZFIN:ZDB-GENE-120328-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
myoscape
Summary
Acts upstream of or within regulation of cardiac muscle contraction. Predicted to be active in cytosol. Orthologous to human STRIP2 (striatin interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See strip2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (4971987..5018734, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (4963419..5010337, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487307 Neighboring gene uncharacterized LOC110439416 Neighboring gene si:dkey-14d8.24 Neighboring gene uncharacterized LOC101884589 Neighboring gene adenosylhomocysteinase like 2b Neighboring gene transmembrane protein 209

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression. Eden M, et al. Nat Commun, 2016 Apr 28. PMID 27122098, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of cardiac muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
striatin-interacting protein 1 homolog
Names
calcium channel-associated protein
fam40b
myocardium-expressed

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    4971987..5018734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009300035.4 → XP_009298310.1  striatin-interacting protein 1 homolog isoform X3

    UniProtKB/TrEMBL
    A0A8M3AR59, E7F9X6
    Related
    ENSDARP00000076427.3, ENSDART00000081990.5
    Conserved Domains (2) summary
    pfam07923
    Location:14 → 274
    N1221; N1221-like protein
    pfam11882
    Location:432 → 762
    DUF3402; Domain of unknown function (DUF3402)

  2. XM_021475408.2 → XP_021331083.1  striatin-interacting protein 1 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8M9PVH8, X1WE96
    Related
    ENSDARP00000128547.1, ENSDART00000154025.3
    Conserved Domains (2) summary
    pfam07923
    Location:43 → 303
    N1221; N1221-like protein
    pfam11882
    Location:444 → 770
    DUF3402; Domain of unknown function (DUF3402)

  3. XM_021475407.2 → XP_021331082.1  striatin-interacting protein 1 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8M9PI62
    Conserved Domains (2) summary
    pfam07923
    Location:43 → 303
    N1221; N1221-like protein
    pfam11882
    Location:461 → 787
    DUF3402; Domain of unknown function (DUF3402)
Nucleotide Protein
Heading Accession and Version

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