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ap5s1 adaptor related protein complex 5 subunit sigma 1 [ Danio rerio (zebrafish) ]

Gene ID: 556111, updated on 2-Nov-2024

Summary

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Official Symbol
ap5s1provided by ZNC
Official Full Name
adaptor related protein complex 5 subunit sigma 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-090313-184
See related
Ensembl:ENSDARG00000076755 AllianceGenome:ZFIN:ZDB-GENE-090313-184
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-146d24.2
Summary
Predicted to be involved in endosomal transport. Predicted to act upstream of or within double-strand break repair via homologous recombination. Predicted to be part of AP-type membrane coat adaptor complex. Predicted to be active in cytosol; late endosome; and lysosome. Orthologous to human AP5S1 (adaptor related protein complex 5 subunit sigma 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See ap5s1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (14902305..14908999, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (14771313..14778007, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487375 Neighboring gene uncharacterized LOC137487377 Neighboring gene glycogenin-1-like Neighboring gene uncharacterized LOC137487335 Neighboring gene cell division cycle 25B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in endosomal transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within endosomal transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of AP-type membrane coat adaptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of AP-type membrane coat adaptor complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
AP-5 complex subunit sigma-1
Names
adaptor-related protein complex 5, sigma 1 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305568.1 → NP_001292497.1  AP-5 complex subunit sigma-1 precursor

    Status: VALIDATED

    Source sequence(s)
    CT573293, EH543915
    UniProtKB/TrEMBL
    A0A8M1P1T9, B8JKA7
    Related
    ENSDARP00000103808.3, ENSDART00000112771.5
    Conserved Domains (1) summary
    pfam15001
    Location:1 → 190
    AP-5_subunit_s1; AP-5 complex subunit sigma-1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    14902305..14908999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials