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hnrnpm heterogeneous nuclear ribonucleoprotein M [ Danio rerio (zebrafish) ]

Gene ID: 555643, updated on 14-Nov-2024

Summary

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Official Symbol
hnrnpmprovided by ZNC
Official Full Name
heterogeneous nuclear ribonucleoprotein Mprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6898
See related
Ensembl:ENSDARG00000061735 AllianceGenome:ZFIN:ZDB-GENE-030131-6898
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fa10g07; wu:fa98b02; si:ch211-197g15.1
Summary
Predicted to enable mRNA binding activity. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human HNRNPM (heterogeneous nuclear ribonucleoprotein M). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See hnrnpm in Genome Data Viewer
Location:
chromosome: 22
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (17531001..17541277)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (17506022..17516299)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene RAB11B, member RAS oncogene family, a Neighboring gene membrane-associated ring finger (C3HC4) 2 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a Neighboring gene glutathione peroxidase 4a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Melanoma genome evolution across species. Kansler ER, et al. BMC Genomics, 2017 Feb 7. PMID 28173755, Free PMC Article
  2. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. Tiefenbach J, et al. PLoS One, 2010 Mar 22. PMID 20339547, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
heterogeneous nuclear ribonucleoprotein M

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256631.1 → NP_001243560.1  heterogeneous nuclear ribonucleoprotein M

    Status: VALIDATED

    Source sequence(s)
    BX649327
    UniProtKB/TrEMBL
    A0A8M1NZJ3
    Conserved Domains (5) summary
    COG0724
    Location:611 → 686
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12657
    Location:49 → 124
    RRM1_hnRNPM; RNA recognition motif 1 in vertebrate heterogeneous nuclear ribonucleoprotein M (hnRNP M)
    cd12659
    Location:204 → 279
    RRM2_hnRNPM; RNA recognition motif 2 in vertebrate heterogeneous nuclear ribonucleoprotein M (hnRNP M)
    cd12661
    Location:610 → 686
    RRM3_hnRNPM; RNA recognition motif 3 in vertebrate heterogeneous nuclear ribonucleoprotein M (hnRNP M)
    pfam11532
    Location:20 → 47
    HnRNP_M; Heterogeneous nuclear ribonucleoprotein M

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    17531001..17541277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170454.5 → XP_005170511.1  heterogeneous nuclear ribonucleoprotein M isoform X1

    UniProtKB/TrEMBL
    A0A0R4IS10, A0A8M2BHR5, F1R2E0
    Related
    ENSDARP00000121443.2, ENSDART00000137689.4
    Conserved Domains (5) summary
    COG0724
    Location:640 → 715
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12657
    Location:49 → 124
    RRM1_hnRNPM; RNA recognition motif 1 in vertebrate heterogeneous nuclear ribonucleoprotein M (hnRNP M)
    cd12659
    Location:233 → 308
    RRM2_hnRNPM; RNA recognition motif 2 in vertebrate heterogeneous nuclear ribonucleoprotein M (hnRNP M)
    cd12661
    Location:639 → 715
    RRM3_hnRNPM; RNA recognition motif 3 in vertebrate heterogeneous nuclear ribonucleoprotein M (hnRNP M)
    pfam11532
    Location:20 → 47
    HnRNP_M; Heterogeneous nuclear ribonucleoprotein M
Nucleotide Protein Strain
Heading Accession and Version

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