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PRNP prion protein (Kanno blood group) [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 554189, updated on 12-May-2024

Summary

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Gene symbol
PRNP
Gene description
prion protein (Kanno blood group)
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See PRNP in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 1 NC_077227.1 (571743309..571745725, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 1 NC_008801.1 (563034828..563066016, complement)

Chromosome 1 - NC_077227.1Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 2 Neighboring gene prion like protein doppel Neighboring gene transforming growth factor alpha Neighboring gene family with sequence similarity 136 member A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The prion protein gene: identifying regulatory signals using marsupial sequence. Premzl M, et al. Gene, 2005 Apr 11. PMID 15777726
  2. Comparative genomic analysis of prion genes. Premzl M, et al. BMC Genomics, 2007 Jan 2. PMID 17199895, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in protein homooligomerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
major prion protein
Names
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
prion protein PrP

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040028.2 → NP_001035117.1  major prion protein precursor

    See identical proteins and their annotated locations for NP_001035117.1

    Status: PROVISIONAL

    Source sequence(s)
    BK005535
    UniProtKB/TrEMBL
    F6QBG5, I7KJS6
    Conserved Domains (3) summary
    smart00157
    Location:26 → 246
    PRP; Major prion protein
    pfam00377
    Location:144 → 246
    Prion; Prion/Doppel alpha-helical domain
    pfam11587
    Location:1 → 29
    Prion_bPrPp; Major prion protein bPrPp - N terminal

RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077227.1 Reference mMonDom1.pri

    Range
    571743309..571745725 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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