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derl2 derlin 2 [ Danio rerio (zebrafish) ]

Gene ID: 554093, updated on 2-Nov-2024

Summary

Official Symbol
derl2provided by ZNC
Official Full Name
derlin 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-90
See related
Ensembl:ENSDARG00000042401 AllianceGenome:ZFIN:ZDB-GENE-050522-90
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110436
Summary
Predicted to enable signal recognition particle binding activity. Predicted to be involved in ERAD pathway and endoplasmic reticulum unfolded protein response. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DERL2 (derlin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See derl2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (58997213..59009175)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (58327504..58339466)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene melanoma cell adhesion molecule a Neighboring gene MIS12 kinetochore complex component Neighboring gene SLP adaptor and CSK interacting membrane protein Neighboring gene rabaptin, RAB GTPase binding effector protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables signal recognition particle binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
derlin-2
Names
Der1-like domain family, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024395.1NP_001019566.1  derlin-2

    See identical proteins and their annotated locations for NP_001019566.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095262
    UniProtKB/TrEMBL
    B2GRJ0, F6NHD9, Q4VBS8
    Related
    ENSDARP00000062174.4, ENSDART00000062175.7
    Conserved Domains (1) summary
    pfam04511
    Location:13203
    DER1; Der1-like family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    58997213..59009175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)