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trmt112 tRNA methyltransferase activator subunit 11-2 [ Danio rerio (zebrafish) ]

Gene ID: 553790, updated on 2-Nov-2024

Summary

Official Symbol
trmt112provided by ZNC
Official Full Name
tRNA methyltransferase activator subunit 11-2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-30
See related
Ensembl:ENSDARG00000071878 AllianceGenome:ZFIN:ZDB-GENE-050522-30
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110652
Summary
Predicted to enable tRNA methyltransferase activator activity. Predicted to be involved in maturation of LSU-rRNA; maturation of SSU-rRNA; and positive regulation of rRNA processing. Predicted to act upstream of or within methylation. Predicted to be part of tRNA (m2G10) methyltransferase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human TRMT112 (tRNA methyltransferase activator subunit 11-2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See trmt112 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (8806422..8814517, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (8500308..8508403, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene potassium channel, subfamily K, member 4a Neighboring gene uncharacterized LOC137487564 Neighboring gene transforming growth factor, beta 5 Neighboring gene autophagy related 2A Neighboring gene nuclear RNA export factor 1a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC110652

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables tRNA methyltransferase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in maturation of LSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of tRNA (m2G10) methyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
multifunctional methyltransferase subunit TRM112-like protein
Names
tRNA methyltransferase 11-2 homolog
tRNA methyltransferase subunit 11-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020752.1NP_001018588.1  multifunctional methyltransferase subunit TRM112-like protein

    See identical proteins and their annotated locations for NP_001018588.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095351
    UniProtKB/TrEMBL
    A0A8M1N6K8, Q503F3
    Related
    ENSDARP00000097448.3, ENSDART00000106670.5
    Conserved Domains (1) summary
    cl01066
    Location:86112
    Trm112p; Trm112p-like protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    8806422..8814517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394892.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    160483..168578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)