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ap5m1 adaptor related protein complex 5 subunit mu 1 [ Danio rerio (zebrafish) ]

Gene ID: 553681, updated on 28-Oct-2024

Summary

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Official Symbol
ap5m1provided by ZNC
Official Full Name
adaptor related protein complex 5 subunit mu 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-231
See related
Ensembl:ENSDARG00000031533 AllianceGenome:ZFIN:ZDB-GENE-050522-231
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112153
Summary
Predicted to be involved in endosomal transport. Predicted to act upstream of or within protein transport. Predicted to be located in membrane. Predicted to be part of AP-type membrane coat adaptor complex. Predicted to be active in cytosol; late endosome; and lysosome. Orthologous to human AP5M1 (adaptor related protein complex 5 subunit mu 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See ap5m1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (44441039..44454020)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (44327282..44340255)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488138 Neighboring gene exocyst complex component 5 Neighboring gene N-alpha-acetyltransferase 30, NatC catalytic subunit Neighboring gene solute carrier family 35 member F4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC112153

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in endosomal transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of AP-type membrane coat adaptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AP-5 complex subunit mu-1
Names
adaptor-related protein complex 5, mu 1 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020654.1 → NP_001018490.1  AP-5 complex subunit mu-1

    See identical proteins and their annotated locations for NP_001018490.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095676
    UniProtKB/TrEMBL
    Q502J2
    Conserved Domains (1) summary
    cd09256
    Location:200 → 467
    AP_MuD_MHD; Mu-homology domain (MHD) of a adaptor protein (AP) encoded by mu-2 related death-inducing gene, MuD (also known as MUDENG)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    44441039..44454020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158894.4 → XP_005158951.1  AP-5 complex subunit mu-1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B5U6
    Related
    ENSDARP00000117738.1, ENSDART00000142123.2
    Conserved Domains (1) summary
    cd09256
    Location:200 → 484
    AP_MuD_MHD; Mu-homology domain (MHD) of a adaptor protein (AP) encoded by mu-2 related death-inducing gene, MuD (also known as MUDENG)
Nucleotide Protein
Heading Accession and Version

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