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ovca2 OVCA2 serine hydrolase domain containing [ Danio rerio (zebrafish) ]

Gene ID: 553576, updated on 18-Sep-2024

Summary

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Official Symbol
ovca2provided by ZNC
Official Full Name
OVCA2 serine hydrolase domain containingprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-115
See related
Ensembl:ENSDARG00000103748 AllianceGenome:ZFIN:ZDB-GENE-050522-115
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110011
Summary
Predicted to enable thiolester hydrolase activity. Predicted to be involved in response to retinoic acid. Predicted to be active in cytoplasm and nucleus. Orthologous to human OVCA2 (OVCA2 serine hydrolase domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See ovca2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (35664129..35668579, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (35720269..35724719, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene microRNA 132-2 Neighboring gene uncharacterized LOC137496601 Neighboring gene microRNA mir-2184 Neighboring gene reticulon-4 receptor-like 1 Neighboring gene uncharacterized LOC137496602 Neighboring gene high mobility group box 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC110011

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables thiolester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
esterase OVCA2
Names
ovarian cancer-associated gene 2 protein homolog
ovarian tumor suppressor candidate 2
NP_001018391.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020555.1 → NP_001018391.1  esterase OVCA2

    See identical proteins and their annotated locations for NP_001018391.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095129
    UniProtKB/Swiss-Prot
    Q503Y4
    Related
    ENSDARP00000133226.1, ENSDART00000167376.2
    Conserved Domains (2) summary
    COG0596
    Location:99 → 210
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    pfam03959
    Location:1 → 219
    FSH1; Serine hydrolase (FSH1)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    35664129..35668579 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q503Y4.1 GenPept UniProtKB/Swiss-Prot:Q503Y4

Gene LinkOut

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