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sqor sulfide quinone oxidoreductase [ Danio rerio (zebrafish) ]

Gene ID: 550580, updated on 2-Nov-2024

Summary

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Official Symbol
sqorprovided by ZNC
Official Full Name
sulfide quinone oxidoreductaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-436
See related
Ensembl:ENSDARG00000017034 AllianceGenome:ZFIN:ZDB-GENE-050417-436
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sqrdl; fj81h04; wu:fj81h04; zgc:113156
Summary
Predicted to enable FAD binding activity and sulfide:quinone oxidoreductase activity. Predicted to be involved in sulfide oxidation, using sulfide:quinone oxidoreductase. Predicted to be active in mitochondrion. Orthologous to human SQOR (sulfide quinone oxidoreductase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See sqor in Genome Data Viewer
Location:
chromosome: 25
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (32473437..32495363)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (32062267..32084406)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene galactokinase 2 Neighboring gene ATPase phospholipid transporting 8B4 Neighboring gene CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a Neighboring gene S-phase cyclin A-associated protein in the ER

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Thermal stress induces a positive phenotypic and molecular feedback loop in zebrafish embryos. Feugere L, et al. J Therm Biol, 2021 Dec. PMID 34863478
  2. Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans. Driessen M, et al. Toxicol Lett, 2014 Oct 1. PMID 25064622
  3. Attributing effects of aqueous C60 nano-aggregates to tetrahydrofuran decomposition products in larval zebrafish by assessment of gene expression. Henry TB, et al. Environ Health Perspect, 2007 Jul. PMID 17637923, Free PMC Article
  4. An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex. Zhang P, et al. Elife, 2016 Jan 14. PMID 26765566, Free PMC Article
  5. Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia. Zhang P, et al. Cell Rep, 2014 Mar 27. PMID 24613356

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables FAD binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables sulfide:quinone oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in sulfide oxidation, using sulfide:quinone oxidoreductase IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sulfide:quinone oxidoreductase, mitochondrial
Names
sulfide quinone reductase-like
NP_001017881.1
XP_021326165.1
XP_068073472.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017881.1 → NP_001017881.1  sulfide:quinone oxidoreductase, mitochondrial

    See identical proteins and their annotated locations for NP_001017881.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093431
    UniProtKB/TrEMBL
    Q566N7
    Related
    ENSDARP00000117779.1, ENSDART00000146451.3
    Conserved Domains (1) summary
    COG0446
    Location:40 → 380
    FadH2; NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    32473437..32495363
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068217371.1 → XP_068073472.1  sulfide:quinone oxidoreductase, mitochondrial isoform X1

  2. XM_021470490.2 → XP_021326165.1  sulfide:quinone oxidoreductase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8M9PYD6
    Conserved Domains (1) summary
    COG0446
    Location:40 → 380
    FadH2; NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism]
Nucleotide Protein Strain
Heading Accession and Version

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