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esd esterase D/formylglutathione hydrolase [ Danio rerio (zebrafish) ]

Gene ID: 550494, updated on 28-Oct-2024

Summary

Official Symbol
esdprovided by ZNC
Official Full Name
esterase D/formylglutathione hydrolaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-328
See related
Ensembl:ENSDARG00000019496 AllianceGenome:ZFIN:ZDB-GENE-050417-328
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb58f05; wu:fb58f05; zgc:111984
Summary
Predicted to enable S-formylglutathione hydrolase activity. Predicted to act upstream of or within formaldehyde catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in female organism; intestinal bulb; and liver. Orthologous to human ESD (esterase D). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See esd in Genome Data Viewer
Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (25172101..25181697, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (25361232..25370828, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene rubicon like autophagy enhancer Neighboring gene leucine-rich repeats and calponin homology (CH) domain containing 1 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a Neighboring gene mediator complex subunit 4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables S-formylglutathione hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables S-formylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within formaldehyde catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
S-formylglutathione hydrolase
NP_001017796.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017796.2NP_001017796.1  S-formylglutathione hydrolase

    See identical proteins and their annotated locations for NP_001017796.1

    Status: VALIDATED

    Source sequence(s)
    BX323457, EH115372, EH478333, EH605044
    UniProtKB/TrEMBL
    A0A0R4IXM0, A0A8N7XJL5, F6NNG0, Q567K2
    Related
    ENSDARP00000024121.5, ENSDART00000012582.7
    Conserved Domains (2) summary
    PLN02442
    Location:2281
    PLN02442; S-formylglutathione hydrolase
    COG0627
    Location:1282
    FrmB; S-formylglutathione hydrolase FrmB [Defense mechanisms]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    25172101..25181697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)