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enpp4 ectonucleotide pyrophosphatase/phosphodiesterase 4 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 550082, updated on 4-Nov-2024

Summary

Official Symbol
enpp4provided by Xenbase
Official Full Name
ectonucleotide pyrophosphatase/phosphodiesterase 4provided by Xenbase
Primary source
Xenbase:XB-GENE-1013025
See related
Ensembl:ENSXETG00000016262 AllianceGenome:Xenbase:XB-GENE-1013025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
E-NPP 4
Summary
Predicted to enable bis(5'-adenosyl)-triphosphatase activity and metal ion binding activity. Predicted to act upstream of or within blood coagulation. Predicted to be located in plasma membrane. Orthologous to human ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See enpp4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (147152028..147162955, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (142898733..142908821, complement)

Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 39 subfamily A member 1 Neighboring gene regulator of calcineurin 2 Neighboring gene aminopeptidase NAALADL1 Neighboring gene tripartite motif-containing 69 gene 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables bis(5'-adenosyl)-triphosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within blood coagulation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
bis(5'-adenosyl)-triphosphatase enpp4
Names
AP3A hydrolase
AP3Aase
E-NPP4
Ectonucleotide pyrophosphatase/phosphodiesterase family member 4
NPP-4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
NP_001017328.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017328.4NP_001017328.2  bis(5'-adenosyl)-triphosphatase enpp4 precursor

    See identical proteins and their annotated locations for NP_001017328.2

    Status: VALIDATED

    Source sequence(s)
    AAMC04000005, BC121205, CX907839, CX907840
    UniProtKB/Swiss-Prot
    Q0VA77
    UniProtKB/TrEMBL
    A0A803J2K9
    Related
    ENSXETP00000035499.4, ENSXETT00000035499.5
    Conserved Domains (1) summary
    pfam01663
    Location:30339
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    147152028..147162955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)