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orc6 origin recognition complex subunit 6 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 549939, updated on 4-Nov-2024

Summary

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Official Symbol
orc6provided by Xenbase
Official Full Name
origin recognition complex subunit 6provided by Xenbase
Primary source
Xenbase:XB-GENE-963541
See related
Ensembl:ENSXETG00000003891 AllianceGenome:Xenbase:XB-GENE-963541
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
orc6l
Summary
Predicted to enable DNA binding activity. Predicted to act upstream of or within DNA replication and cilium assembly. Predicted to be located in nucleus. Predicted to be part of nuclear origin of replication recognition complex. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 3. Orthologous to human ORC6 (origin recognition complex subunit 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See orc6 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (73076696..73085042)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (25049910..25059000)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene exosome complex component MTR3 pseudogene Neighboring gene histamine H3 receptor Neighboring gene VPS35 retromer complex component Neighboring gene myosin light chain kinase 3 Neighboring gene chromosome 4 C16orf87 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cilium assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of nuclear origin of replication recognition complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
origin recognition complex subunit 6
Names
origin recognition complex, subunit 6 like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017185.2 → NP_001017185.1  origin recognition complex subunit 6

    See identical proteins and their annotated locations for NP_001017185.1

    Status: PROVISIONAL

    Source sequence(s)
    CR760635
    UniProtKB/TrEMBL
    F6TNG5, F7BSI3, Q28I20
    Conserved Domains (3) summary
    cd11583
    Location:94 → 186
    Orc6_mid; Middle domain of the origin recognition complex subunit 6
    cd16075
    Location:199 → 251
    ORC6_CTD; C-terminal domain of the eukaryotic origin recognition complex subunit ORC6
    pfam05460
    Location:6 → 95
    ORC6; Origin recognition complex subunit 6 (ORC6)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    73076696..73085042
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012961183.3 → XP_012816637.1  origin recognition complex subunit 6 isoform X1

    See identical proteins and their annotated locations for XP_012816637.1

    UniProtKB/TrEMBL
    F6TNG5, F7BSI3, Q28I20
    Conserved Domains (3) summary
    cd11583
    Location:94 → 186
    Orc6_mid; Middle domain of the origin recognition complex subunit 6
    cd16075
    Location:199 → 251
    ORC6_CTD; C-terminal domain of the eukaryotic origin recognition complex subunit ORC6
    pfam05460
    Location:6 → 95
    ORC6; Origin recognition complex subunit 6 (ORC6)

  2. XM_012961181.3 → XP_012816635.1  origin recognition complex subunit 6 isoform X1

    See identical proteins and their annotated locations for XP_012816635.1

    UniProtKB/TrEMBL
    F6TNG5, F7BSI3, Q28I20
    Related
    ENSXETP00000008444.2, ENSXETT00000008444.4
    Conserved Domains (3) summary
    cd11583
    Location:94 → 186
    Orc6_mid; Middle domain of the origin recognition complex subunit 6
    cd16075
    Location:199 → 251
    ORC6_CTD; C-terminal domain of the eukaryotic origin recognition complex subunit ORC6
    pfam05460
    Location:6 → 95
    ORC6; Origin recognition complex subunit 6 (ORC6)

  3. XM_012961182.3 → XP_012816636.1  origin recognition complex subunit 6 isoform X1

    See identical proteins and their annotated locations for XP_012816636.1

    UniProtKB/TrEMBL
    F6TNG5, F7BSI3, Q28I20
    Conserved Domains (3) summary
    cd11583
    Location:94 → 186
    Orc6_mid; Middle domain of the origin recognition complex subunit 6
    cd16075
    Location:199 → 251
    ORC6_CTD; C-terminal domain of the eukaryotic origin recognition complex subunit ORC6
    pfam05460
    Location:6 → 95
    ORC6; Origin recognition complex subunit 6 (ORC6)
Nucleotide Protein Strain
Heading Accession and Version

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