tuba4b tubulin alpha 4b [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: tuba4bprovided by Xenbase
Official Full Name: tubulin alpha 4bprovided by Xenbase
Primary source: Xenbase:XB-GENE-489927
See related: Ensembl:ENSXETG00000047851 AllianceGenome:Xenbase:XB-GENE-489927
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: tuba; tuba1; tuba4; tuba4a
Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 22. Orthologous to human TUBA4A (tubulin alpha 4a). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	9	NC_030685.2 (83910640..83919592)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	9	NC_030685.1 (78578350..78587314)

Chromosome 9 - NC_030685.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of cytoskeleton	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in microtubule cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within microtubule-based process	IEA Inferred from Electronic Annotation more info
involved_in mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: tubulin alpha chain

Names: alpha tubulin; tubulin, alpha 1 (testis specific)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001016694.2 → NP_001016694.1 tubulin alpha chain

See identical proteins and their annotated locations for NP_001016694.1

Status: PROVISIONAL

Source sequence(s)

CR760170

UniProtKB/Swiss-Prot

Q28IX8

UniProtKB/TrEMBL

A0A803JZF2, B7ZTG2

Related

ENSXETP00000106751.1, ENSXETT00000106577.1

Conserved Domains (2) summary

PTZ00335
Location:1 → 439

PTZ00335; tubulin alpha chain; Provisional

cd02186
Location:2 → 435

alpha_tubulin; The alpha-tubulin family

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

83910640..83919592

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012970434.3 → XP_012825888.1 tubulin alpha chain isoform X1

UniProtKB/TrEMBL

A0A803JZF2, A0A803K8T7

Related

ENSXETP00000116804.1, ENSXETT00000117178.1

Conserved Domains (1) summary

PTZ00335
Location:5 → 442

PTZ00335; tubulin alpha chain; Provisional