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LOX1.1 seed linoleate 13S-lipoxygenase-1 [ Glycine max (soybean) ]

Gene ID: 547923, updated on 7-Dec-2023

Summary

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Gene symbol
LOX1.1
Gene description
seed linoleate 13S-lipoxygenase-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Glycine max
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade; NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine; Glycine subgen. Soja
Also known as
L-1; Lx1
Annotation information
Annotation category: suggests misassembly
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Genomic context

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See LOX1.1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
9
Annotation release Status Assembly Chr Location
104 current Glycine_max_v4.0 (GCF_000004515.6) 13 NC_038249.2 (43135621..43139890)
103 previous assembly Glycine_max_v2.1 (GCF_000004515.5) 13 NC_038249.1 (43769022..43773290)

Chromosome 13 - NC_038249.2Genomic Context describing neighboring genes Neighboring gene lipoxygenase-2 Neighboring gene microRNA MIR1532 Neighboring gene lipoxygenase Neighboring gene lipoxygenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative kinetic isotope effects on first- and second-order rate constants of soybean lipoxygenase variants uncover a substrate-binding network. Hu S, et al. J Biol Chem, 2019 Nov 29. PMID 31624150, Free PMC Article
  2. Control of the Position of Oxygen Delivery in Soybean Lipoxygenase-1 by Amino Acid Side Chains within a Gas Migration Channel. Collazo L, et al. J Biol Chem, 2016 Apr 22. PMID 26867580, Free PMC Article
  3. Active Site Dynamical Effects in the Hydrogen Transfer Rate-limiting Step in the Catalysis of Linoleic Acid by Soybean Lipoxygenase-1 (SLO-1): Primary and Secondary Isotope Contributions. Phatak P, et al. J Phys Chem B, 2015 Jul 30. PMID 26079999
  4. Fluctuations of an exposed π-helix involved in lipoxygenase substrate recognition. Bradshaw MD, et al. Biochemistry, 2014 Aug 12. PMID 25036469, Free PMC Article
  5. Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1. Tomchick DR, et al. Biochemistry, 2001 Jun 26. PMID 11412104

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Comparative kinetic isotope effects on first- and second-order rate constants of soybean lipoxygenase variants uncover a substrate-binding network.
    Title: Comparative kinetic isotope effects on first- and second-order rate constants of soybean lipoxygenase variants uncover a substrate-binding network.
  2. Soybean 13-lipoxygenase-1 specifically oxidized 20:2, 22:2, and linoleate into (omega6S)-hydroperoxides. [13-LO-1] [LO-1]
    Title: Specificity of oxidation of linoleic acid homologs by plant lipoxygenases.
  3. Control of the Position of Oxygen Delivery in Soybean Lipoxygenase-1 by Amino Acid Side Chains within a Gas Migration Channel.
    Title: Control of the Position of Oxygen Delivery in Soybean Lipoxygenase-1 by Amino Acid Side Chains within a Gas Migration Channel.
  4. Catalysis of Linoleic Acid by Soybean Lipoxygenase-1
    Title: Active Site Dynamical Effects in the Hydrogen Transfer Rate-limiting Step in the Catalysis of Linoleic Acid by Soybean Lipoxygenase-1 (SLO-1): Primary and Secondary Isotope Contributions.
  5. a pi-helix in the second helix is highly dynamic and is the site where lipid chains penetrate to inner helices that outline the substrate pocket
    Title: Fluctuations of an exposed π-helix involved in lipoxygenase substrate recognition.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
seed linoleate 13S-lipoxygenase-1
Names
lipoxygenase 1
lipoxygenase L-1
mutant lipoxygenase 1
seed linoleate 9S-lipoxygenase-1
NP_001236153.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001249224.2 → NP_001236153.2  seed linoleate 13S-lipoxygenase-1

    Status: VALIDATED

    Source sequence(s)
    ACUP04004818, J02795
    UniProtKB/Swiss-Prot
    P08170
    UniProtKB/TrEMBL
    B3TDK4, D6PAW3
    Conserved Domains (1) summary
    PLN02337
    Location:3 → 839
    PLN02337; lipoxygenase

RefSeqs of Annotated Genomes: Glycine max Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Glycine_max_v4.0 Primary Assembly

Genomic

  1. NC_038249.2 Reference Glycine_max_v4.0 Primary Assembly

    Range
    43135621..43139890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P08170.2 GenPept UniProtKB/Swiss-Prot:P08170

Gene LinkOut

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