U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Klhl33 kelch-like 33 [ Mus musculus (house mouse) ]

Gene ID: 546611, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Klhl33provided by MGI
Official Full Name
kelch-like 33provided by MGI
Primary source
MGI:MGI:3644593
See related
Ensembl:ENSMUSG00000090799 AllianceGenome:MGI:3644593
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG546611
Summary
Orthologous to human KLHL33 (kelch like family member 33). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in cerebellum adult (RPKM 5.2), heart adult (RPKM 2.7) and 8 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Klhl33 in Genome Data Viewer
Location:
14 C1; 14 26.29 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51126038..51134940, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (50888581..50897483, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene telomerase associated protein 1 Neighboring gene predicted gene, 52116 Neighboring gene STARR-positive B cell enhancer ABC_E8557 Neighboring gene predicted gene, 26782 Neighboring gene Apex1 promoter region Neighboring gene O-sialoglycoprotein endopeptidase Neighboring gene apurinic/apyrimidinic endonuclease 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
kelch-like protein 33

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166651.2 → NP_001160123.1  kelch-like protein 33 isoform 2

    See identical proteins and their annotated locations for NP_001160123.1

    Status: INFERRED

    Source sequence(s)
    AC027184
    Consensus CDS
    CCDS56952.1
    UniProtKB/TrEMBL
    G3UW92
    Related
    ENSMUSP00000129810.2, ENSMUST00000164415.2
    Conserved Domains (6) summary
    smart00612
    Location:323 → 369
    Kelch; Kelch domain
    smart00225
    Location:1 → 70
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:75 → 175
    BACK; BTB And C-terminal Kelch
    TIGR03547
    Location:253 → 505
    muta_rot_YjhT; mutatrotase, YjhT family
    sd00038
    Location:312 → 355
    Kelch; KELCH repeat [structural motif]
    pfam01344
    Location:358 → 393
    Kelch_1; Kelch motif

  2. NM_001370764.1 → NP_001357693.1  kelch-like protein 33 isoform 1

    Status: INFERRED

    Source sequence(s)
    AC027184
    Consensus CDS
    CCDS88651.1
    UniProtKB/TrEMBL
    A0A2I3BRZ3
    Related
    ENSMUSP00000154785.2, ENSMUST00000227271.2
    Conserved Domains (3) summary
    PHA03098
    Location:319 → 738
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:572 → 615
    Kelch; KELCH repeat [structural motif]
    cl38908
    Location:220 → 337
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    51126038..51134940 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools