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Stk19 serine/threonine kinase 19 [ Mus musculus (house mouse) ]

Gene ID: 54402, updated on 2-Nov-2024

Summary

Official Symbol
Stk19provided by MGI
Official Full Name
serine/threonine kinase 19provided by MGI
Primary source
MGI:MGI:1860085
See related
Ensembl:ENSMUSG00000061207 AllianceGenome:MGI:1860085
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G11; RP1
Summary
Predicted to enable ATP binding activity and histone H2AS1 kinase activity. Predicted to be involved in positive regulation of Ras protein signal transduction. Predicted to be located in cytoplasm and nuclear speck. Orthologous to human STK19 (serine/threonine kinase 19). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in adrenal adult (RPKM 37.1), duodenum adult (RPKM 18.4) and 28 other tissues See more
Orthologs
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Genomic context

See Stk19 in Genome Data Viewer
Location:
17 B1; 17 18.38 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (35042969..35055879, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (34823993..34836903, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene tenascin XA (pseudogene) Neighboring gene Cyp21a1 5' regulatory region Neighboring gene cytochrome P450, family 21, subfamily a, polypeptide 1 Neighboring gene STARR-seq mESC enhancer starr_42439 Neighboring gene complement C4A (Rodgers blood group) Neighboring gene C4a promoter region Neighboring gene C4a androgen-responsive enhancer Neighboring gene STARR-positive B cell enhancer ABC_E8920 Neighboring gene decapping exoribonuclease Neighboring gene SKI2 subunit of superkiller complex Neighboring gene microRNA 6971

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables histone H2AS1 kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of Ras protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of Ras protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
inactive serine/threonine-protein kinase 19
Names
serine/threonine-protein kinase 19
NP_062315.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019442.3NP_062315.1  inactive serine/threonine-protein kinase 19

    See identical proteins and their annotated locations for NP_062315.1

    Status: PROVISIONAL

    Source sequence(s)
    CT573030
    Consensus CDS
    CCDS28659.1
    UniProtKB/Swiss-Prot
    O70347, Q9JHN8
    UniProtKB/TrEMBL
    Q3TG64
    Related
    ENSMUSP00000076686.6, ENSMUST00000077477.12
    Conserved Domains (1) summary
    pfam10494
    Location:27251
    Stk19; Serine-threonine protein kinase 19

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    35042969..35055879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)