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zgc:110540 zgc:110540 [ Danio rerio (zebrafish) ]

Gene ID: 541538, updated on 17-Aug-2024

Summary

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Official Symbol
zgc:110540provided by ZNC
Official Full Name
zgc:110540provided by ZNC
Primary source
ZFIN:ZDB-GENE-050327-77
See related
Ensembl:ENSDARG00000054929 AllianceGenome:ZFIN:ZDB-GENE-050327-77
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Dck; dck2; wu:fe11h12; wu:fj05e11; zgc:109951
Summary
Predicted to enable deoxynucleoside kinase activity. Predicted to act upstream of or within nucleobase-containing compound metabolic process and phosphorylation. Predicted to be active in mitochondrion. Is expressed in proliferative region. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 21
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26485852..26490146, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26449157..26453451, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E binding protein 3 Neighboring gene ankyrin repeat and KH domain containing 1 Neighboring gene transfer RNA serine (anticodon GCU) Neighboring gene CD248 molecule, endosialin b Neighboring gene Ras converting CAAX endopeptidase 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming. Murphy PJ, et al. Cell, 2018 Feb 22. PMID 29456083
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC174279

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables deoxycytidine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables deoxyguanosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables deoxynucleoside kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within nucleobase-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
deoxynucleoside kinase
Names
deoxycytidine kinase
NP_001014374.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014352.2 → NP_001014374.1  deoxynucleoside kinase

    Status: PREDICTED

    Source sequence(s)
    BC091889
    UniProtKB/TrEMBL
    Q58EI2
    Related
    ENSDARP00000004823.6, ENSDART00000009889.7
    Conserved Domains (2) summary
    COG0125
    Location:20 → 261
    Tmk; Thymidylate kinase [Nucleotide transport and metabolism]
    pfam01712
    Location:25 → 262
    dNK; Deoxynucleoside kinase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    26485852..26490146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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