aoc2 amine oxidase copper containing 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aoc2provided by ZNC
Official Full Name: amine oxidase copper containing 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-050320-133
See related: Ensembl:ENSDARG00000014646 AllianceGenome:ZFIN:ZDB-GENE-050320-133
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: aoc3; fa94a08; fe14c05; wu:fa94a08; wu:fe14c05; zgc:113006
Summary: Predicted to enable copper ion binding activity; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; and quinone binding activity. Predicted to be involved in amine metabolic process. Predicted to act upstream of or within visual perception. Orthologous to human AOC2 (amine oxidase copper containing 2) and AOC3 (amine oxidase copper containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (32924186..32927605, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (32792472..32795891, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI105815 (e-PCR)
- UniSTS:206849

fe14c05.x1 (e-PCR)
- UniSTS:196187

fa94a08.y1 (e-PCR)
- UniSTS:189686

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables copper ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	IEA Inferred from Electronic Annotation more info
enables primary methylamine oxidase activity	IEA Inferred from Electronic Annotation more info
enables quinone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within amine metabolic process	IEA Inferred from Electronic Annotation more info
involved_in amine metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: retina-specific copper amine oxidase

Names: amine oxidase, copper containing 3

NP_001013573.3

EC 1.4.3.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013555.3 → NP_001013573.3 retina-specific copper amine oxidase

Status: PROVISIONAL

Source sequence(s)

CT583642

UniProtKB/TrEMBL

A0A8M1N4I9

Related

ENSDARP00000121793.1, ENSDART00000140117.3

Conserved Domains (4) summary

PRK11504
Location:58 → 709

tynA; tyramine oxidase; Provisional

pfam01179
Location:307 → 710

Cu_amine_oxid; Copper amine oxidase, enzyme domain

pfam02727
Location:61 → 144

Cu_amine_oxidN2; Copper amine oxidase, N2 domain

pfam02728
Location:194 → 258

Cu_amine_oxidN3; Copper amine oxidase, N3 domain