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SF1 splicing factor 1 [ Bos taurus (domestic cattle) ]

Gene ID: 541229, updated on 10-Oct-2024

Summary

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Official Symbol
SF1provided by VGNC
Official Full Name
splicing factor 1provided by VGNC
Primary source
VGNC:VGNC:34505
See related
BGD:BT12100; Ensembl:ENSBTAG00000001035
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See SF1 in Genome Data Viewer
Location:
chromosome: 29
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (43002797..43016681, complement)

Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene RAS guanyl releasing protein 2 Neighboring gene glycogen phosphorylase, muscle associated Neighboring gene mitogen-activated protein kinase kinase kinase kinase 2 Neighboring gene menin 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC142950, MGC157322

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
splicing factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081614.1 → NP_001075083.1  splicing factor 1

    See identical proteins and their annotated locations for NP_001075083.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133313
    UniProtKB/TrEMBL
    A0AAF6DLG5, A2VDM7, E1B903
    Related
    ENSBTAP00000001376.6, ENSBTAT00000001376.7
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    43002797..43016681 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024987277.2 → XP_024843045.1  splicing factor 1 isoform X8

    UniProtKB/TrEMBL
    A0AAA9SN47
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  2. XM_024987275.2 → XP_024843043.1  splicing factor 1 isoform X6

    UniProtKB/TrEMBL
    A0AAA9SN47
    Related
    ENSBTAP00000084239.1, ENSBTAT00000124987.1
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  3. XM_005227172.5 → XP_005227229.1  splicing factor 1 isoform X9

    See identical proteins and their annotated locations for XP_005227229.1

    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  4. XM_005227166.5 → XP_005227223.1  splicing factor 1 isoform X4

    See identical proteins and their annotated locations for XP_005227223.1

    UniProtKB/TrEMBL
    A0AAF6DLG5
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  5. XM_005227171.5 → XP_005227228.1  splicing factor 1 isoform X7

    UniProtKB/TrEMBL
    A0AAA9SN47
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  6. XM_024987274.2 → XP_024843042.1  splicing factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1M720
    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  7. XM_024987273.2 → XP_024843041.1  splicing factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1M720
    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  8. XM_005227165.5 → XP_005227222.1  splicing factor 1 isoform X3

    Conserved Domains (3) summary
    smart00343
    Location:394 → 409
    ZnF_C2HC; zinc finger
    cd02395
    Location:253 → 371
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam16275
    Location:134 → 246
    SF1-HH; Splicing factor 1 helix-hairpin domain

  9. XM_059882996.1 → XP_059738979.1  splicing factor 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9RZ74
    Related
    ENSBTAP00000076613.1, ENSBTAT00000097406.1

  10. XM_059882995.1 → XP_059738978.1  splicing factor 1 isoform X1

    UniProtKB/TrEMBL
    A0AAA9S424
    Related
    ENSBTAP00000078549.1, ENSBTAT00000133157.1
Nucleotide Protein Strain
Heading Accession and Version

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