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KCNIP2 potassium voltage-gated channel interacting protein 2 [ Bos taurus (domestic cattle) ]

Gene ID: 540895, updated on 4-Oct-2024

Summary

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Official Symbol
KCNIP2provided by VGNC
Official Full Name
potassium voltage-gated channel interacting protein 2provided by VGNC
Primary source
VGNC:VGNC:30451
See related
Ensembl:ENSBTAG00000016343
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See KCNIP2 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (22551084..22569885, complement)

Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene nucleophosmin/nucleoplasmin 3 Neighboring gene O-GlcNAcase Neighboring gene armadillo like helical domain containing 3 Neighboring gene HPS6 biogenesis of lysosomal organelles complex 2 subunit 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC155025

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of voltage-gated potassium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A-type potassium channel modulatory protein KCNIP2; Kv channel-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102250.1 → NP_001095720.1  A-type potassium channel modulatory protein KCNIP2

    See identical proteins and their annotated locations for NP_001095720.1

    Status: PROVISIONAL

    Source sequence(s)
    BC149230
    UniProtKB/TrEMBL
    A6QPA9, F1N410
    Conserved Domains (2) summary
    COG5126
    Location:38 → 204
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:89 → 151
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    22551084..22569885 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005225595.5 → XP_005225652.1  Kv channel-interacting protein 2 isoform X2

    See identical proteins and their annotated locations for XP_005225652.1

    UniProtKB/TrEMBL
    F1N410
    Related
    ENSBTAP00000089314.1, ENSBTAT00000117569.1
    Conserved Domains (1) summary
    COG5126
    Location:93 → 259
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  2. XM_010819913.4 → XP_010818215.1  Kv channel-interacting protein 2 isoform X1

    Conserved Domains (2) summary
    COG5126
    Location:93 → 251
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:144 → 206
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  3. XM_005225605.5 → XP_005225662.1  Kv channel-interacting protein 2 isoform X7

    See identical proteins and their annotated locations for XP_005225662.1

    UniProtKB/TrEMBL
    A0AAA9RTR0
    Related
    ENSBTAP00000076431.1, ENSBTAT00000127376.1
    Conserved Domains (1) summary
    COG5126
    Location:108 → 274
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  4. XM_005225603.5 → XP_005225660.1  Kv channel-interacting protein 2 isoform X5

    UniProtKB/TrEMBL
    F1N410
    Conserved Domains (1) summary
    COG5126
    Location:43 → 201
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  5. XM_005225604.5 → XP_005225661.1  Kv channel-interacting protein 2 isoform X6

    See identical proteins and their annotated locations for XP_005225661.1

    UniProtKB/TrEMBL
    F1N410
    Related
    ENSBTAP00000021742.6, ENSBTAT00000021742.7
    Conserved Domains (1) summary
    COG5126
    Location:43 → 209
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  6. XM_005225600.5 → XP_005225657.1  Kv channel-interacting protein 2 isoform X3

    See identical proteins and their annotated locations for XP_005225657.1

    UniProtKB/TrEMBL
    A0AAA9S0U8
    Conserved Domains (1) summary
    COG5126
    Location:48 → 206
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  7. XM_005225601.5 → XP_005225658.1  Kv channel-interacting protein 2 isoform X4

    See identical proteins and their annotated locations for XP_005225658.1

    UniProtKB/TrEMBL
    A0AAA9SYI1, F1N410
    Related
    ENSBTAP00000090427.1, ENSBTAT00000092758.1
    Conserved Domains (1) summary
    COG5126
    Location:48 → 214
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  8. XM_005225599.5 → XP_005225656.1  Kv channel-interacting protein 2 isoform X8

    See identical proteins and their annotated locations for XP_005225656.1

    UniProtKB/TrEMBL
    A0AAA9SUU7, F1N410
    Related
    ENSBTAP00000087743.1, ENSBTAT00000112661.1
    Conserved Domains (1) summary
    COG5126
    Location:53 → 219
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
Nucleotide Protein Strain
Heading Accession and Version

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