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GRM1 glutamate metabotropic receptor 1 [ Bos taurus (domestic cattle) ]

Gene ID: 540485, updated on 4-Oct-2024

Summary

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Official Symbol
GRM1provided by VGNC
Official Full Name
glutamate metabotropic receptor 1provided by VGNC
Primary source
VGNC:VGNC:53794
See related
BGD:BT12087; Ensembl:ENSBTAG00000044181
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See GRM1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (83287291..83715752)

Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene SNF2 histone linker PHD RING helicase Neighboring gene uncharacterized LOC132346129 Neighboring gene RAB32, member RAS oncogene family Neighboring gene F-box only protein 25-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Heterodimerization of calcium sensing receptors with metabotropic glutamate receptors in neurons. Gama L, et al. J Biol Chem, 2001 Oct 19. PMID 11489900
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables adenylate cyclase inhibiting G protein-coupled glutamate receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled glutamate receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metabotropic glutamate receptor 1
Names
glutamate receptor, metabotropic 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206004.1 → NP_001192933.1  metabotropic glutamate receptor 1

    See identical proteins and their annotated locations for NP_001192933.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000009
    UniProtKB/TrEMBL
    A0A3Q1LK20
    Related
    ENSBTAP00000056935.1, ENSBTAT00000085376.1
    Conserved Domains (5) summary
    cd06374
    Location:36 → 510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604 → 837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77 → 485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521 → 570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    pfam10606
    Location:1142 → 1192
    GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    83287291..83715752
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005211024.5 → XP_005211081.1  metabotropic glutamate receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_005211081.1

    UniProtKB/TrEMBL
    A0A3Q1LK20
    Conserved Domains (5) summary
    cd06374
    Location:36 → 510
    PBP1_mGluR_groupI; Ligand binding domain of the group I metabotropic glutamate receptor
    pfam00003
    Location:604 → 837
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77 → 485
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:521 → 570
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    pfam10606
    Location:1142 → 1192
    GluR_Homer-bdg; Homer-binding domain of metabotropic glutamate receptor

  2. XM_059889816.1 → XP_059745799.1  metabotropic glutamate receptor 1 isoform X2

    UniProtKB/TrEMBL
    F1MDE0
    Related
    ENSBTAP00000053724.4, ENSBTAT00000061121.4
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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