HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: HSD3B7provided by VGNC
Official Full Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7provided by VGNC
Primary source: VGNC:VGNC:29978
See related: BGD:BT29970; Ensembl:ENSBTAG00000002346
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 25

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	25	NC_037352.1 (27119070..27122803)

Chromosome 25 - NC_037352.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in steroid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 3 beta-hydroxysteroid dehydrogenase type 7

Names: 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase

NP_001029868.1

EC 1.1.1.181

XP_015315868.1

EC 1.1.1.181

XP_059737393.1

EC 1.1.1.181

XP_059737394.1

EC 1.1.1.181

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001034696.1 → NP_001029868.1 3 beta-hydroxysteroid dehydrogenase type 7

See identical proteins and their annotated locations for NP_001029868.1

Status: PROVISIONAL

Source sequence(s)

BC105259

UniProtKB/TrEMBL

Q3MHF2

Related

ENSBTAP00000003028.5, ENSBTAT00000003028.7

Conserved Domains (2) summary

cd09811
Location:11 → 361

3b-HSD_HSDB1_like_SDR_e; human 3beta-HSD (hydroxysteroid dehydrogenase) and HSD3B1(delta 5-delta 4-isomerase)-like, extended (e) SDRs

pfam01073
Location:13 → 291

3Beta_HSD; 3-beta hydroxysteroid dehydrogenase/isomerase family

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

Range

27119070..27122803

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015460382.3 → XP_015315868.1 3 beta-hydroxysteroid dehydrogenase type 7 isoform X1

Conserved Domains (2) summary

cd09811
Location:106 → 454

3b-HSD_HSDB1_like_SDR_e; human 3beta-HSD (hydroxysteroid dehydrogenase) and HSD3B1(delta 5-delta 4-isomerase)-like, extended (e) SDRs

pfam01073
Location:109 → 384

3Beta_HSD; 3-beta hydroxysteroid dehydrogenase/isomerase family
XM_059881410.1 → XP_059737393.1 3 beta-hydroxysteroid dehydrogenase type 7 isoform X2
XM_059881411.1 → XP_059737394.1 3 beta-hydroxysteroid dehydrogenase type 7 isoform X3