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PARD6B par-6 family cell polarity regulator beta [ Bos taurus (domestic cattle) ]

Gene ID: 539687, updated on 4-Oct-2024

Summary

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Official Symbol
PARD6Bprovided by VGNC
Official Full Name
par-6 family cell polarity regulator betaprovided by VGNC
Primary source
VGNC:VGNC:32584
See related
BGD:BT26092; Ensembl:ENSBTAG00000021601
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PARD6B in Genome Data Viewer
Location:
chromosome: 13
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (78707002..78721682)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase non-receptor type 1 Neighboring gene RIPOR family member 3 Neighboring gene uncharacterized LOC132346986 Neighboring gene breast carcinoma amplified sequence 4 Neighboring gene microRNA mir-6527 Neighboring gene activity dependent neuroprotector homeobox

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC149024

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein kinase C binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in centrosome cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cellular localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
partitioning defective 6 homolog beta
Names
PAR-6 beta
par-6 partitioning defective 6 homolog beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098104.1 → NP_001091573.1  partitioning defective 6 homolog beta

    See identical proteins and their annotated locations for NP_001091573.1

    Status: PROVISIONAL

    Source sequence(s)
    BC140683
    UniProtKB/TrEMBL
    A0A3Q1LS90, A5D7U3
    Related
    ENSBTAP00000028786.4, ENSBTAT00000028786.6
    Conserved Domains (2) summary
    cd06403
    Location:17 → 96
    PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
    cd00992
    Location:156 → 247
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    78707002..78721682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials