CYP27B1 cytochrome P450 family 27 subfamily B member 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CYP27B1provided by VGNC
Official Full Name: cytochrome P450 family 27 subfamily B member 1provided by VGNC
Primary source: VGNC:VGNC:110245
See related: BGD:BT27845; Ensembl:ENSBTAG00000016906
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	5	NC_037332.1 (55698420..55703344)

Chromosome 5 - NC_037332.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that in tissue and secreted cells from the infected mammary glands, 25-hydroxyvitamin D(3) 1alpha-hydroxylase (1alpha-OHase; CYP27B1) gene expression was significantly increased compared to expression in tissue and cells from the healthy mammary tissue.
Title: In vivo activation of the intracrine vitamin D pathway in innate immune cells and mammary tissue during a bacterial infection.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in C21-steroid hormone biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to peptide hormone stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cholesterol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cortisol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glucocorticoid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

Names: cytochrome P450, family 27, subfamily B, polypeptide 1

NP_001179213.1

EC 1.14.15.18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.