U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GDF5 growth differentiation factor 5 [ Bos taurus (domestic cattle) ]

Gene ID: 539559, updated on 4-Oct-2024

Summary

Official Symbol
GDF5provided by VGNC
Official Full Name
growth differentiation factor 5provided by VGNC
Primary source
VGNC:VGNC:29303
See related
BGD:BT11881; Ensembl:ENSBTAG00000004429
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See GDF5 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (64681475..64685232, complement)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83 member C Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 1 Neighboring gene transfer RNA methionine (anticodon CAU) Neighboring gene centrosomal protein 250 Neighboring gene uncharacterized LOC104973870

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
growth/differentiation factor 5

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192273.1NP_001179202.1  growth/differentiation factor 5 precursor

    See identical proteins and their annotated locations for NP_001179202.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000013
    UniProtKB/TrEMBL
    F1MT44
    Related
    ENSBTAP00000005807.5, ENSBTAT00000005807.7
    Conserved Domains (2) summary
    smart00204
    Location:398499
    TGFB; Transforming growth factor-beta (TGF-beta) family
    pfam00688
    Location:143342
    TGFb_propeptide; TGF-beta propeptide

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    64681475..64685232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)