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CERS2 ceramide synthase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 539223, updated on 12-Oct-2024

Summary

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Official Symbol
CERS2provided by VGNC
Official Full Name
ceramide synthase 2provided by VGNC
Primary source
VGNC:VGNC:27224
See related
BGD:BT26529; Ensembl:ENSBTAG00000000099
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
LASS2
Orthologs
human mouse all
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Genomic context

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See CERS2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (19793120..19802016)

Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene prune exopolyphosphatase 1 Neighboring gene MINDY lysine 48 deubiquitinase 1 Neighboring gene annexin A9 Neighboring gene SET domain bifurcated histone lysine methyltransferase 1 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene cortexin domain containing 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC126981

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ceramide synthase 2
Names
LAG1 homolog, ceramide synthase 2
LAG1 longevity assurance 2
LAG1 longevity assurance homolog 2
sphingosine N-acyltransferase CERS2
tumor metastasis-suppressor gene 1 protein
very-long-chain ceramide synthase CERS2
NP_001029839.1
XP_005203977.1
XP_024845379.1
XP_024845380.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034667.1 → NP_001029839.1  ceramide synthase 2

    See identical proteins and their annotated locations for NP_001029839.1

    Status: PROVISIONAL

    Source sequence(s)
    BC103330
    UniProtKB/Swiss-Prot
    Q3ZBF8
    UniProtKB/TrEMBL
    A0AAF6YH00
    Related
    ENSBTAP00000000109.6, ENSBTAT00000000109.7
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    19793120..19802016
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024989612.2 → XP_024845380.1  ceramide synthase 2 isoform X1

    UniProtKB/Swiss-Prot
    Q3ZBF8
    UniProtKB/TrEMBL
    A0AAF6YH00
    Related
    ENSBTAP00000103338.1, ENSBTAT00000126401.1
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  2. XM_024989611.2 → XP_024845379.1  ceramide synthase 2 isoform X1

    UniProtKB/Swiss-Prot
    Q3ZBF8
    UniProtKB/TrEMBL
    A0AAF6YH00
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  3. XM_005203920.5 → XP_005203977.1  ceramide synthase 2 isoform X1

    See identical proteins and their annotated locations for XP_005203977.1

    UniProtKB/Swiss-Prot
    Q3ZBF8
    UniProtKB/TrEMBL
    A0AAF6YH00
    Conserved Domains (2) summary
    smart00724
    Location:131 → 332
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:71 → 128
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3ZBF8.1 GenPept UniProtKB/Swiss-Prot:Q3ZBF8

Gene LinkOut

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