MEGF10 multiple EGF like domains 10 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: MEGF10provided by VGNC
Official Full Name: multiple EGF like domains 10provided by VGNC
Primary source: VGNC:VGNC:31375
See related: BGD:BT10843; Ensembl:ENSBTAG00000000329
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	7	NC_037334.1 (26554472..26736801, complement)

Chromosome 7 - NC_037334.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables scavenger receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: multiple epidermal growth factor-like domains protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001046451.2 → NP_001039916.2 multiple epidermal growth factor-like domains protein 10

Status: VALIDATED

Source sequence(s)

AAFC03024715, AAFC03024717, AAFC03024718, AAFC03049192, AAFC03049194, AAFC03049195

UniProtKB/TrEMBL

F1MET4

Related

ENSBTAP00000068877.1, ENSBTAT00000071608.2

Conserved Domains (2) summary

pfam07546
Location:32 → 99

EMI; EMI domain

cl21504
Location:542 → 587

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

Range

26554472..26736801 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005209094.5 → XP_005209151.1 multiple epidermal growth factor-like domains protein 10 isoform X1

See identical proteins and their annotated locations for XP_005209151.1

UniProtKB/TrEMBL

A0A3Q1M5E6, F1MET4

Conserved Domains (3) summary

pfam00053
Location:281 → 326

Laminin_EGF; Laminin EGF domain

pfam07546
Location:32 → 99

EMI; EMI domain

cl21504
Location:542 → 587

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...