KCNJ12 potassium inwardly rectifying channel subfamily J member 12 [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: KCNJ12
Gene description: potassium inwardly rectifying channel subfamily J member 12
See related: Ensembl:ENSBTAG00000020061
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: IRK2; KIR2.2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	19	NC_037346.1 (35328104..35365897)

Chromosome 19 - NC_037346.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Copy Number Variation CNV1 and CNV 2 in KCNJ12 are associated with growth traits in two cattle populations and may be used as candidates for marker-assisted selection and breeding management in cattle.
Title: Distribution and association study in copy number variation of KCNJ12 gene across four Chinese cattle populations.

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General gene information

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Markers

KCNJ12_870 (e-PCR)
- UniSTS:277420

KCNJ12_V177 (e-PCR)
- UniSTS:277420

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables inward rectifier potassium channel activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in potassium ion import across plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ATP-sensitive inward rectifier potassium channel 12

Names: potassium channel, inwardly rectifying subfamily J member 12; potassium inwardly-rectifying channel J12; potassium voltage-gated channel subfamily J member 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024690.2 → NP_001019861.2 ATP-sensitive inward rectifier potassium channel 12

See identical proteins and their annotated locations for NP_001019861.2

Status: PROVISIONAL

Source sequence(s)

BC133380

UniProtKB/TrEMBL

A2VDS5

Related

ENSBTAP00000077541.1, ENSBTAT00000119931.1

Conserved Domains (2) summary

pfam01007
Location:47 → 374

IRK; Inward rectifier potassium channel

pfam08466
Location:3 → 46

IRK_N; Inward rectifier potassium channel N-terminal

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

Range

35328104..35365897

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005220595.5 → XP_005220652.2 ATP-sensitive inward rectifier potassium channel 12 isoform X1

UniProtKB/Swiss-Prot

Q4TZY1

Related

ENSBTAP00000086488.1, ENSBTAT00000114144.1

Conserved Domains (3) summary

pfam01007
Location:47 → 187

IRK; Inward rectifier potassium channel

pfam08466
Location:2 → 46

IRK_N; Inward rectifier potassium channel N-terminal

pfam17655
Location:194 → 366

IRK_C; Inward rectifier potassium channel C-terminal domain