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KATNAL1 katanin catalytic subunit A1 like 1 [ Bos taurus (domestic cattle) ]

Gene ID: 537739, updated on 10-Oct-2024

Summary

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Official Symbol
KATNAL1provided by VGNC
Official Full Name
katanin catalytic subunit A1 like 1provided by VGNC
Primary source
VGNC:VGNC:30406
See related
BGD:BT29587; Ensembl:ENSBTAG00000009340
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See KATNAL1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (30478410..30537549)

Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346756 Neighboring gene uncharacterized LOC132346757 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene transfer RNA glycine (anticodon UCC)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Association between an alternative promoter polymorphism and sperm deformity rate is due to modulation of the expression of KATNAL1 transcripts in Chinese Holstein bulls. Zhang X, et al. Anim Genet, 2014 Oct. PMID 24990491
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. alternative promoter polymorphisms produce splice variants of KATNAL1, which causes sperm deformity
    Title: Association between an alternative promoter polymorphism and sperm deformity rate is due to modulation of the expression of KATNAL1 transcripts in Chinese Holstein bulls.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule severing ATPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in microtubule severing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
katanin p60 ATPase-containing subunit A-like 1
Names
katanin p60 subunit A-like 1-AS protein
NP_001179847.1
XP_005213723.1
XP_010809026.1
XP_010809027.1
XP_010809028.1
XP_010809029.1
XP_010809030.1
XP_024855692.1
XP_059748067.1
XP_059748068.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192918.1 → NP_001179847.1  katanin p60 ATPase-containing subunit A-like 1

    See identical proteins and their annotated locations for NP_001179847.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000012
    UniProtKB/TrEMBL
    E1BHF2, F1MAX6, W0GI54
    Related
    ENSBTAP00000012297.7, ENSBTAT00000012297.7
    Conserved Domains (1) summary
    COG0464
    Location:188 → 483
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    30478410..30537549
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010810724.4 → XP_010809026.1  katanin p60 ATPase-containing subunit A-like 1 isoform X1

    See identical proteins and their annotated locations for XP_010809026.1

    UniProtKB/TrEMBL
    E1BHF2, F1MAX6, W0GI54
    Conserved Domains (1) summary
    COG0464
    Location:188 → 483
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

  2. XM_010810725.4 → XP_010809027.1  katanin p60 ATPase-containing subunit A-like 1 isoform X1

    See identical proteins and their annotated locations for XP_010809027.1

    UniProtKB/TrEMBL
    E1BHF2, F1MAX6, W0GI54
    Conserved Domains (1) summary
    COG0464
    Location:188 → 483
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

  3. XM_059892084.1 → XP_059748067.1  katanin p60 ATPase-containing subunit A-like 1 isoform X1

    UniProtKB/TrEMBL
    E1BHF2, W0GI54

  4. XM_005213666.5 → XP_005213723.1  katanin p60 ATPase-containing subunit A-like 1 isoform X1

    See identical proteins and their annotated locations for XP_005213723.1

    UniProtKB/TrEMBL
    E1BHF2, F1MAX6, W0GI54
    Conserved Domains (1) summary
    COG0464
    Location:188 → 483
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

  5. XM_010810726.4 → XP_010809028.1  katanin p60 ATPase-containing subunit A-like 1 isoform X1

    See identical proteins and their annotated locations for XP_010809028.1

    UniProtKB/TrEMBL
    E1BHF2, F1MAX6, W0GI54
    Conserved Domains (1) summary
    COG0464
    Location:188 → 483
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

  6. XM_010810727.4 → XP_010809029.1  katanin p60 ATPase-containing subunit A-like 1 isoform X1

    See identical proteins and their annotated locations for XP_010809029.1

    UniProtKB/TrEMBL
    E1BHF2, F1MAX6, W0GI54
    Conserved Domains (1) summary
    COG0464
    Location:188 → 483
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

  7. XM_010810728.4 → XP_010809030.1  katanin p60 ATPase-containing subunit A-like 1 isoform X3

    See identical proteins and their annotated locations for XP_010809030.1

    UniProtKB/TrEMBL
    A0AAF6DLH5
    Conserved Domains (3) summary
    pfam09336
    Location:324 → 362
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:276 → 320
    AAA_lid_3; AAA+ lid domain
    cd19522
    Location:83 → 252
    RecA-like_KTNA1; Katanin p60 ATPase-containing subunit A1

  8. XM_024999924.2 → XP_024855692.1  katanin p60 ATPase-containing subunit A-like 1 isoform X3

    UniProtKB/TrEMBL
    A0AAF6DLH5
    Conserved Domains (3) summary
    pfam09336
    Location:324 → 362
    Vps4_C; Vps4 C terminal oligomerization domain
    pfam17862
    Location:276 → 320
    AAA_lid_3; AAA+ lid domain
    cd19522
    Location:83 → 252
    RecA-like_KTNA1; Katanin p60 ATPase-containing subunit A1

  9. XM_059892085.1 → XP_059748068.1  katanin p60 ATPase-containing subunit A-like 1 isoform X2

RNA

  1. XR_236621.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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