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ACSL4 acyl-CoA synthetase long chain family member 4 [ Bos taurus (domestic cattle) ]

Gene ID: 536628, updated on 10-Oct-2024

Summary

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Official Symbol
ACSL4provided by VGNC
Official Full Name
acyl-CoA synthetase long chain family member 4provided by VGNC
Primary source
VGNC:VGNC:25566
See related
BGD:BT26375; Ensembl:ENSBTAG00000018986
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
FACL4
Orthologs
human mouse all
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Genomic context

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See ACSL4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (58032529..58110133, complement)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene nuclear transport factor 2 like export factor 2 Neighboring gene potassium voltage-gated channel subfamily E regulatory subunit 5 Neighboring gene ferritin heavy chain-like Neighboring gene uncharacterized LOC112445128 Neighboring gene transmembrane protein 164 Neighboring gene microRNA mir-652

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene. Fan Y, et al. Genes (Basel), 2020 Nov 16. PMID 33207796, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.
    Title: Identification of Milk Fat Metabolism-Related Pathways of the Bovine Mammary Gland during Mid and Late Lactation and Functional Verification of the ACSL4 Gene.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate-CoA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in long-chain fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-chain fatty-acyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
long-chain-fatty-acid--CoA ligase 4
Names
fatty-acid-Coenzyme A ligase, long-chain 4
XP_002699912.1
XP_015317069.1
XP_015317071.1
XP_015317072.1
XP_015317073.1
XP_024844495.1
XP_059739656.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    58032529..58110133 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015461586.3 → XP_015317072.1  long-chain-fatty-acid--CoA ligase 4 isoform X2

    UniProtKB/TrEMBL
    A0AAA9TAL4, A7E3D9
    Conserved Domains (2) summary
    cd05927
    Location:80 → 667
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)
    PLN02387
    Location:24 → 667
    PLN02387; long-chain-fatty-acid-CoA ligase family protein

  2. XM_002699866.6 → XP_002699912.1  long-chain-fatty-acid--CoA ligase 4 isoform X2

    See identical proteins and their annotated locations for XP_002699912.1

    UniProtKB/TrEMBL
    A0AAA9TAL4, A7E3D9
    Related
    ENSBTAP00000093927.1, ENSBTAT00000122507.1
    Conserved Domains (2) summary
    cd05927
    Location:80 → 667
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)
    PLN02387
    Location:24 → 667
    PLN02387; long-chain-fatty-acid-CoA ligase family protein

  3. XM_024988727.2 → XP_024844495.1  long-chain-fatty-acid--CoA ligase 4 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LZ55, A7E3D9
    Conserved Domains (1) summary
    cd05927
    Location:121 → 708
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)

  4. XM_015461583.3 → XP_015317069.1  long-chain-fatty-acid--CoA ligase 4 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LZ55, A7E3D9
    Related
    ENSBTAP00000060970.1, ENSBTAT00000070050.2
    Conserved Domains (1) summary
    cd05927
    Location:121 → 708
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)

  5. XM_059883673.1 → XP_059739656.1  long-chain-fatty-acid--CoA ligase 4 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LZ55

  6. XM_015461587.3 → XP_015317073.1  long-chain-fatty-acid--CoA ligase 4 isoform X2

    UniProtKB/TrEMBL
    A0AAA9TAL4, A7E3D9
    Conserved Domains (2) summary
    cd05927
    Location:80 → 667
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)
    PLN02387
    Location:24 → 667
    PLN02387; long-chain-fatty-acid-CoA ligase family protein

  7. XM_015461585.2 → XP_015317071.1  long-chain-fatty-acid--CoA ligase 4 isoform X2

    UniProtKB/TrEMBL
    A0AAA9TAL4, A7E3D9
    Conserved Domains (2) summary
    cd05927
    Location:80 → 667
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)
    PLN02387
    Location:24 → 667
    PLN02387; long-chain-fatty-acid-CoA ligase family protein
Nucleotide Protein Strain
Heading Accession and Version

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