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ITGB8 integrin subunit beta 8 [ Bos taurus (domestic cattle) ]

Gene ID: 536286, updated on 10-Oct-2024

Summary

Official Symbol
ITGB8provided by VGNC
Official Full Name
integrin subunit beta 8provided by VGNC
Primary source
VGNC:VGNC:30333
See related
BGD:BT10180; Ensembl:ENSBTAG00000003709
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See ITGB8 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (29021938..29120852)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene MET transcriptional regulator MACC1 Neighboring gene large ribosomal subunit protein eL6-like Neighboring gene uncharacterized LOC132345074 Neighboring gene uncharacterized LOC132345073 Neighboring gene ATP binding cassette subfamily B member 5 Neighboring gene Sp8 transcription factor

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
integrin beta-8
Names
integrin, beta 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192875.3NP_001179804.1  integrin beta-8 precursor

    See identical proteins and their annotated locations for NP_001179804.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000004
    UniProtKB/TrEMBL
    A0AAA9SZ14, F1MVW3
    Related
    ENSBTAP00000004833.4, ENSBTAT00000004833.6
    Conserved Domains (1) summary
    smart00187
    Location:54468
    INB; Integrin beta subunits (N-terminal portion of extracellular region)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    29021938..29120852
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059885664.1XP_059741647.1  integrin beta-8 isoform X3

  2. XM_059885663.1XP_059741646.1  integrin beta-8 isoform X1

  3. XM_015468532.3XP_015324018.1  integrin beta-8 isoform X2

    Conserved Domains (1) summary
    cl00057
    Location:1334
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...