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PPP2R1A protein phosphatase 2 scaffold subunit Aalpha [ Bos taurus (domestic cattle) ]

Gene ID: 535321, updated on 5-Oct-2024

Summary

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Official Symbol
PPP2R1Aprovided by VGNC
Official Full Name
protein phosphatase 2 scaffold subunit Aalphaprovided by VGNC
Primary source
VGNC:VGNC:33253
See related
BGD:BT24237; Ensembl:ENSBTAG00000019851
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PPP2R1A in Genome Data Viewer
Location:
chromosome: 18
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (58087796..58110746)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 350 Neighboring gene zinc finger protein 350 Neighboring gene vomeronasal 1 receptor bosTauV1R417 Neighboring gene vomeronasal 1 receptor bosTauV1R414 Neighboring gene vomeronasal type-1 receptor 4-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A. Shern JF, et al. J Biol Chem, 2003 Oct 17. PMID 12912990
  2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC128399

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of protein phosphatase type 2A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Names
medium tumor antigen-associated 61 kDa protein
protein phosphatase 2, regulatory subunit A, alpha
NP_001032554.1
XP_059732818.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037477.1 → NP_001032554.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

    See identical proteins and their annotated locations for NP_001032554.1

    Status: PROVISIONAL

    Source sequence(s)
    BC108103
    UniProtKB/Swiss-Prot
    Q32PI5
    Related
    ENSBTAP00000026449.5, ENSBTAT00000026449.6
    Conserved Domains (5) summary
    COG1413
    Location:165 → 422
    HEAT; HEAT repeat [General function prediction only]
    pfam13513
    Location:179 → 231
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:488 → 583
    HEAT_2; HEAT repeats
    sd00044
    Location:245 → 269
    HEAT; HEAT repeat [structural motif]
    cl21454
    Location:396 → 454
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    58087796..58110746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059876835.1 → XP_059732818.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q32PI5.1 GenPept UniProtKB/Swiss-Prot:Q32PI5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials