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KLHL3 kelch like family member 3 [ Bos taurus (domestic cattle) ]

Gene ID: 533364, updated on 10-Oct-2024

Summary

Official Symbol
KLHL3provided by VGNC
Official Full Name
kelch like family member 3provided by VGNC
Primary source
VGNC:VGNC:30657
See related
BGD:BT19188; Ensembl:ENSBTAG00000002796
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See KLHL3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (49065397..49342365, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345832 Neighboring gene SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 Neighboring gene microRNA mir-874 Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene heterogeneous nuclear ribonucleoprotein A0 Neighboring gene polycystin 2 like 2, transient receptor potential cation channel Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene myotilin Neighboring gene family with sequence similarity 13 member B

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in monoatomic ion homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein K48-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in renal sodium ion absorption IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
kelch-like protein 3
Names
kelch-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    49065397..49342365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059888747.1XP_059744730.1  kelch-like protein 3 isoform X1

  2. XM_059888748.1XP_059744731.1  kelch-like protein 3 isoform X1

  3. XM_059888749.1XP_059744732.1  kelch-like protein 3 isoform X3

    UniProtKB/TrEMBL
    A0AAF6YKC9
    Related
    ENSBTAP00000003625.7, ENSBTAT00000003625.7
  4. XM_002689207.7XP_002689253.2  kelch-like protein 3 isoform X2

    See identical proteins and their annotated locations for XP_002689253.2

    UniProtKB/Swiss-Prot
    F1MBP6
    UniProtKB/TrEMBL
    A0A3Q1LXU6
    Related
    ENSBTAP00000097590.1, ENSBTAT00000103433.1
    Conserved Domains (5) summary
    smart00612
    Location:491537
    Kelch; Kelch domain
    PHA03098
    Location:47566
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:431476
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:40144
    BTB; BTB/POZ domain
    pfam07707
    Location:152254
    BACK; BTB And C-terminal Kelch