ACTC1 actin alpha cardiac muscle 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: ACTC1provided by VGNC
Official Full Name: actin alpha cardiac muscle 1provided by VGNC
Primary source: VGNC:VGNC:25574
See related: BGD:BT10983; Ensembl:ENSBTAG00000005714
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: ACTC
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	10	NC_037337.1 (30288631..30293908, complement)

Chromosome 10 - NC_037337.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tm affects the conformation of actin so as to increase the area of hydrophobic interaction between actin and myosin molecules
Title: Temperature-dependence of isometric tension and cross-bridge kinetics of cardiac muscle fibers reconstituted with a tropomyosin internal deletion mutant.

Submit: New GeneRIF Correction

General gene information

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Markers

Actb (e-PCR), detects polymorphism
- UniSTS:496720

PMC23952P1 (e-PCR)
- UniSTS:272216

GDB:186852 (e-PCR)
- UniSTS:64858

PMC149351P1 (e-PCR)
- UniSTS:271029

UniSTS:478948 (e-PCR)
- UniSTS:478948

Actc1 (e-PCR), detects polymorphism
- UniSTS:478948

ACTC (e-PCR), detects polymorphism
- UniSTS:266226

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables myosin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin filament organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in actin-myosin filament sliding	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heart contraction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in actin filament	IEA Inferred from Electronic Annotation more info	PubMed
located_in sarcomere	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: actin, alpha cardiac muscle 1

Names: alpha-cardiac actin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.