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KMT5A lysine methyltransferase 5A [ Bos taurus (domestic cattle) ]

Gene ID: 532622, updated on 4-Oct-2024

Summary

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Official Symbol
KMT5Aprovided by VGNC
Official Full Name
lysine methyltransferase 5Aprovided by VGNC
Primary source
VGNC:VGNC:53910
See related
BGD:BT11335; Ensembl:ENSBTAG00000000139
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
SETD8
Orthologs
human mouse all
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Genomic context

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See KMT5A in Genome Data Viewer
Location:
chromosome: 17
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (52209613..52228187, complement)

Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein U11/U12 subunit 35 Neighboring gene Rab interacting lysosomal protein like 2 Neighboring gene U6 spliceosomal RNA Neighboring gene strawberry notch homolog 1 Neighboring gene uncharacterized LOC132342611 Neighboring gene cyclin dependent kinase 2 associated protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC134426

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H4K20 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
N-lysine methyltransferase KMT5A
Names
H4-K20-HMTase KMT5A
H4-K20-HMTase SETD8
N-lysine methyltransferase SETD8
PR-Set7
PR/SET domain-containing protein 07
PR/SET07
SET domain containing (lysine methyltransferase) 8
SET domain-containing 8
SET domain-containing protein 8
histone-lysine N-methyltransferase KMT5A
histone-lysine N-methyltransferase SETD8
lysine-specific methylase 5A
NP_001039795.1
XP_024833095.2
XP_024833096.1
XP_024833097.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001046330.1 → NP_001039795.1  N-lysine methyltransferase KMT5A

    See identical proteins and their annotated locations for NP_001039795.1

    Status: PROVISIONAL

    Source sequence(s)
    BC110189
    UniProtKB/Swiss-Prot
    Q2YDJ8
    UniProtKB/TrEMBL
    F1MFC8
    Related
    ENSBTAP00000000160.7, ENSBTAT00000000160.7
    Conserved Domains (1) summary
    smart00317
    Location:224 → 338
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    52209613..52228187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024977327.2 → XP_024833095.2  N-lysine methyltransferase KMT5A isoform X1

    UniProtKB/TrEMBL
    A0AAA9TJT6
    Related
    ENSBTAP00000098621.1, ENSBTAT00000108316.1

  2. XM_024977328.2 → XP_024833096.1  N-lysine methyltransferase KMT5A isoform X2

    UniProtKB/TrEMBL
    A0AAF6ZQG1, F1MFC8
    Related
    ENSBTAP00000055591.3, ENSBTAT00000063474.3
    Conserved Domains (1) summary
    smart00317
    Location:218 → 332
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain

  3. XM_024977329.2 → XP_024833097.1  N-lysine methyltransferase KMT5A isoform X3

    UniProtKB/TrEMBL
    A0AAA9STW5
    Related
    ENSBTAP00000089865.1, ENSBTAT00000097736.1
    Conserved Domains (2) summary
    smart00317
    Location:167 → 281
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cl26939
    Location:58 → 152
    DEXDc; DEAD-like helicases superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2YDJ8.1 GenPept UniProtKB/Swiss-Prot:Q2YDJ8

Gene LinkOut

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