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CISD1 CDGSH iron sulfur domain 1 [ Bos taurus (domestic cattle) ]

Gene ID: 531444, updated on 10-Oct-2024

Summary

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Official Symbol
CISD1provided by VGNC
Official Full Name
CDGSH iron sulfur domain 1provided by VGNC
Primary source
VGNC:VGNC:27371
See related
BGD:BT13996; Ensembl:ENSBTAG00000003634
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See CISD1 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (745914..764085, complement)

Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 D1 Neighboring gene aldo-keto reductase family 1, member B1 (aldose reductase) pseudogene Neighboring gene inositol polyphosphate multikinase Neighboring gene nuclear receptor coactivator 4-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a novel mitochondrial protein ("mitoNEET") cross-linked specifically by a thiazolidinedione photoprobe. Colca JR, et al. Am J Physiol Endocrinol Metab, 2004 Feb. PMID 14570702
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. mitoNEET is located in the mitochondrial fraction of bovine brain.
    Title: Identification of a novel mitochondrial protein ("mitoNEET") cross-linked specifically by a thiazolidinedione photoprobe.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC128185

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CDGSH iron-sulfur domain-containing protein 1
Names
cysteine transaminase CISD1
mitoNEET
NP_001029229.1
XP_005225399.1
XP_015316043.1
XP_024841431.1
XP_024841432.1
XP_024841433.1
XP_059737857.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034057.1 → NP_001029229.1  CDGSH iron-sulfur domain-containing protein 1

    See identical proteins and their annotated locations for NP_001029229.1

    Status: PROVISIONAL

    Source sequence(s)
    BC103105
    UniProtKB/Swiss-Prot
    Q3ZBU2
    UniProtKB/TrEMBL
    A0AAA9SCT9
    Related
    ENSBTAP00000004739.4, ENSBTAT00000004739.5
    Conserved Domains (2) summary
    smart00704
    Location:53 → 91
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:10 → 39
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    745914..764085 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015460557.3 → XP_015316043.1  CDGSH iron-sulfur domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9SCT9, A0AAA9TSD4
    Related
    ENSBTAP00000101292.1, ENSBTAT00000127190.1
    Conserved Domains (2) summary
    smart00704
    Location:58 → 96
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:15 → 44
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus

  2. XM_059881874.1 → XP_059737857.1  CDGSH iron-sulfur domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9TSD4

  3. XM_024985663.2 → XP_024841431.1  CDGSH iron-sulfur domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9SCT9, A0AAA9TSD4
    Conserved Domains (2) summary
    smart00704
    Location:58 → 96
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:15 → 44
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus

  4. XM_024985664.2 → XP_024841432.1  CDGSH iron-sulfur domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9SCT9, A0AAA9TSD4
    Conserved Domains (2) summary
    smart00704
    Location:58 → 96
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:15 → 44
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus

  5. XM_024985665.1 → XP_024841433.1  CDGSH iron-sulfur domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9SCT9, A0AAA9TSD4
    Conserved Domains (2) summary
    smart00704
    Location:58 → 96
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:15 → 44
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus

  6. XM_005225342.5 → XP_005225399.1  CDGSH iron-sulfur domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005225399.1

    Conserved Domains (2) summary
    smart00704
    Location:78 → 116
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:35 → 64
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3ZBU2.1 GenPept UniProtKB/Swiss-Prot:Q3ZBU2

Gene LinkOut

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Molecular Biology Databases
Research Materials