FFAR3 free fatty acid receptor 3 [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: FFAR3
Gene description: free fatty acid receptor 3
See related: BGD:BT16987; Ensembl:ENSBTAG00000013791
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: GPR41
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	18	NC_037345.1 (46054918..46061309)

Chromosome 18 - NC_037345.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

An inverse regulation of FFAR2 and FFAR3 expression over time and both receptors also showed an inverse mRNA abundance as induced by different portions of concentrate. Thus, indicating divergent nutrient sensing of both receptors in adipose tissues (AT) during the transition period.
Title: Expression of metabolic sensing receptors in adipose tissues of periparturient dairy cows with differing extent of negative energy balance.
GPR41 gene contains 3 exons and its transcription is initiated at 2 leader exons, generating 2 GPR41 mRNA variants differing in the 5' untranslated region
Title: Identification and characterization of the bovine G protein-coupled receptor GPR41 and GPR43 genes.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to fatty acid	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: free fatty acid receptor 3

Names: G protein-coupled receptor 41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145233.1 → NP_001138705.1 free fatty acid receptor 3

See identical proteins and their annotated locations for NP_001138705.1

Status: PROVISIONAL

Source sequence(s)

FJ562213

UniProtKB/TrEMBL

B9VJW0, E1B873, F1MAX9, G3MZT6

Related

ENSBTAP00000055089.2, ENSBTAT00000063172.3

Conserved Domains (1) summary

pfam00001
Location:68 → 275

7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

Range

46054918..46061309

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015458060.3 → XP_015313546.1 free fatty acid receptor 3 isoform X1

Conserved Domains (1) summary

pfam00001
Location:107 → 314

7tm_1; 7 transmembrane receptor (rhodopsin family)