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BECN1 beclin 1 [ Bos taurus (domestic cattle) ]

Gene ID: 527278, updated on 4-Oct-2024

Summary

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Official Symbol
BECN1provided by VGNC
Official Full Name
beclin 1provided by VGNC
Primary source
VGNC:VGNC:26463
See related
BGD:BT26123; Ensembl:ENSBTAG00000019914
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
ATG6
Orthologs
human mouse all
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Genomic context

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See BECN1 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (42837030..42848106, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene WNK lysine deficient protein kinase 4 Neighboring gene cytochrome c oxidase assembly factor 3 Neighboring gene cyclin N-terminal domain containing 1 Neighboring gene proteasome activator subunit 3 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene amine oxidase copper containing 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Foot-and-mouth disease virus modulates cellular vimentin for virus survival. Gladue DP, et al. J Virol, 2013 Jun. PMID 23576498, Free PMC Article
  2. Foot-and-mouth disease virus nonstructural protein 2C interacts with Beclin1, modulating virus replication. Gladue DP, et al. J Virol, 2012 Nov. PMID 22933281, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC126978

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nitrogen starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in late endosome to vacuole transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beclin-1
Names
beclin 1, autophagy related
coiled-coil myosin-like BCL2-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033627.2 → NP_001028799.1  beclin-1

    See identical proteins and their annotated locations for NP_001028799.1

    Status: PROVISIONAL

    Source sequence(s)
    BC102177
    UniProtKB/Swiss-Prot
    Q4A1L4
    UniProtKB/TrEMBL
    A0A3Q1MEG2
    Related
    ENSBTAP00000026531.4, ENSBTAT00000026531.6
    Conserved Domains (2) summary
    pfam15285
    Location:105 → 127
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
    pfam04111
    Location:133 → 443
    APG6; Autophagy protein Apg6

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    42837030..42848106 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024980228.2 → XP_024835996.1  beclin-1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MEG2
    Conserved Domains (2) summary
    pfam15285
    Location:128 → 150
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
    pfam04111
    Location:156 → 466
    APG6; Autophagy protein Apg6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4A1L4.1 GenPept UniProtKB/Swiss-Prot:Q4A1L4

Gene LinkOut

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