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CDKN2B cyclin dependent kinase inhibitor 2B [ Bos taurus (domestic cattle) ]

Gene ID: 527124, updated on 18-Aug-2024

Summary

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Gene symbol
CDKN2B
Gene description
cyclin dependent kinase inhibitor 2B
See related
BGD:BT11457
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
MTS2
Orthologs
human mouse all
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Genomic context

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See CDKN2B in Genome Data Viewer
Location:
chromosome: 8
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (22082124..22087035)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1-gamma-like Neighboring gene uncharacterized LOC132345927 Neighboring gene microRNA mir-2285cd Neighboring gene cyclin dependent kinase inhibitor 2A Neighboring gene uncharacterized LOC132345928 Neighboring gene transfer RNA cysteine (anticodon ACA)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase 4 inhibitor B
Names
p14-INK4b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075894.1 → NP_001069362.1  cyclin-dependent kinase 4 inhibitor B

    See identical proteins and their annotated locations for NP_001069362.1

    Status: PROVISIONAL

    Source sequence(s)
    BC105392
    UniProtKB/Swiss-Prot
    Q2KJD8
    Conserved Domains (3) summary
    cd00204
    Location:14 → 125
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:11 → 103
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:7 → 37
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    22082124..22087035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2KJD8.1 GenPept UniProtKB/Swiss-Prot:Q2KJD8

Gene LinkOut

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Molecular Biology Databases
Research Materials