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GTPV_gp011 EIF2a-like PKR inhibitor [ Goatpox virus Pellor ]

Gene ID: 5228348, updated on 18-Aug-2023

Summary

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Gene symbol
GTPV_gp011
Gene description
EIF2a-like PKR inhibitor
Locus tag
GTPV_gp011
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Goatpox virus Pellor (strain: Pellor)
Lineage
Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes; Chitovirales; Poxviridae; Chordopoxvirinae; Capripoxvirus
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Genomic context

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Sequence:
NC_004003.1 (9466..9735, complement)

NC_004003.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled chemokine receptor-like protein Neighboring gene ankyrin repeat protein Neighboring gene IL-18 binding protein Neighboring gene hypothetical protein Neighboring gene anti-apoptotic membrane protein Neighboring gene dUTPase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004003.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genomes of sheeppox and goatpox viruses. Tulman ER, et al. J Virol, 2002 Jun. PMID 12021338, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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  • Old name: GTPV-Pellor-011

General protein information

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Preferred Names
EIF2a-like PKR inhibitor
YP_001293205.1
  • EIF2a-like PKR inhibitor; acts to inhibit protein kinase PKR (EIF2AK2) and plays a major role virus resistance to interferon; similar to vaccinia virus Copenhagen K3L; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004003.1 Reference assembly

    Range
    9466..9735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_001293205.1 EIF2a-like PKR inhibitor [Goatpox virus Pellor]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A075CI46, A0A1B2LPI7, A0A2Z4XFL8, A0A5C0PT20
    Conserved Domains (1) summary
    cl09927
    Location:1 → 85
    S1_like; Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains ...

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