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ACER1 alkaline ceramidase 1 [ Bos taurus (domestic cattle) ]

Gene ID: 518021, updated on 4-Oct-2024

Summary

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Official Symbol
ACER1provided by VGNC
Official Full Name
alkaline ceramidase 1provided by VGNC
Primary source
VGNC:VGNC:25536
See related
BGD:BT22592; Ensembl:ENSBTAG00000008095
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
ASAH3
Orthologs
human mouse all
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Genomic context

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See ACER1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (18075496..18132770)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene alkB homolog 7 Neighboring gene persephin Neighboring gene caseinolytic mitochondrial matrix peptidase proteolytic subunit Neighboring gene uncharacterized LOC132345711 Neighboring gene MLLT1 super elongation complex subunit Neighboring gene acyl-CoA synthetase bubblegum family member 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC151717

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alkaline ceramidase 1
Names
N-acylsphingosine amidohydrolase (alkaline ceramidase) 3
NP_001096724.1
XP_010805226.1
XP_010805227.1
XP_010805228.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103254.1 → NP_001096724.1  alkaline ceramidase 1

    See identical proteins and their annotated locations for NP_001096724.1

    Status: PROVISIONAL

    Source sequence(s)
    BC149050
    UniProtKB/TrEMBL
    A6QNX6
    Conserved Domains (1) summary
    pfam05875
    Location:3 → 112
    Ceramidase; Ceramidase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    18075496..18132770
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010806925.4 → XP_010805227.1  alkaline ceramidase 1 isoform X2

    Conserved Domains (1) summary
    pfam05875
    Location:1 → 212
    Ceramidase; Ceramidase

  2. XM_010806924.4 → XP_010805226.1  alkaline ceramidase 1 isoform X1

    UniProtKB/TrEMBL
    F1MGH9
    Related
    ENSBTAP00000010648.5, ENSBTAT00000010648.6
    Conserved Domains (1) summary
    pfam05875
    Location:3 → 255
    Ceramidase; Ceramidase

  3. XM_010806926.4 → XP_010805228.1  alkaline ceramidase 1 isoform X3

    Conserved Domains (1) summary
    pfam05875
    Location:3 → 209
    Ceramidase; Ceramidase
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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