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TDP1 tyrosyl-DNA phosphodiesterase 1 [ Bos taurus (domestic cattle) ]

Gene ID: 517053, updated on 17-Aug-2024

Summary

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Official Symbol
TDP1provided by VGNC
Official Full Name
tyrosyl-DNA phosphodiesterase 1provided by VGNC
Primary source
VGNC:VGNC:35713
See related
BGD:BT19046; Ensembl:ENSBTAG00000013138
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See TDP1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (101635810..101708726)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101907299 Neighboring gene EF-hand calcium binding domain 11 Neighboring gene potassium two pore domain channel subfamily K member 13 Neighboring gene uncharacterized LOC112448536 Neighboring gene uncharacterized LOC101907747 Neighboring gene proteasome 26S subunit, ATPase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-tyrosyl-DNA phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in single strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosyl-DNA phosphodiesterase 1
NP_001180084.1
XP_024853291.1
XP_024853292.1
XP_059746359.1
XP_059746360.1
XP_059746361.1
XP_059746362.1
XP_059746363.1
XP_059746364.1
XP_059746365.1
XP_059746366.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001193155.1 → NP_001180084.1  tyrosyl-DNA phosphodiesterase 1

    See identical proteins and their annotated locations for NP_001180084.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000010
    UniProtKB/TrEMBL
    F1MST1
    Related
    ENSBTAP00000017463.6, ENSBTAT00000017463.7
    Conserved Domains (1) summary
    pfam06087
    Location:170 → 586
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    101635810..101708726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059890378.1 → XP_059746361.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    F1MST1

  2. XM_059890376.1 → XP_059746359.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    F1MST1

  3. XM_059890383.1 → XP_059746366.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    F1MST1

  4. XM_059890379.1 → XP_059746362.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    F1MST1

  5. XM_059890377.1 → XP_059746360.1  tyrosyl-DNA phosphodiesterase 1 isoform X3

    UniProtKB/TrEMBL
    F1MST1

  6. XM_059890381.1 → XP_059746364.1  tyrosyl-DNA phosphodiesterase 1 isoform X5

    UniProtKB/TrEMBL
    A0AAA9T7W1

  7. XM_059890382.1 → XP_059746365.1  tyrosyl-DNA phosphodiesterase 1 isoform X5

    UniProtKB/TrEMBL
    A0AAA9T7W1

  8. XM_059890380.1 → XP_059746363.1  tyrosyl-DNA phosphodiesterase 1 isoform X4

    UniProtKB/TrEMBL
    A0AAA9T7W1

  9. XM_024997523.2 → XP_024853291.1  tyrosyl-DNA phosphodiesterase 1 isoform X1

    UniProtKB/TrEMBL
    F1MST1
    Conserved Domains (1) summary
    pfam06087
    Location:205 → 636
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

  10. XM_024997524.2 → XP_024853292.1  tyrosyl-DNA phosphodiesterase 1 isoform X2

    UniProtKB/TrEMBL
    A0AAA9S356, F1MST1
    Related
    ENSBTAP00000076535.1, ENSBTAT00000134536.1
    Conserved Domains (1) summary
    pfam06087
    Location:205 → 621
    Tyr-DNA_phospho; Tyrosyl-DNA phosphodiesterase

RNA

  1. XR_009496033.1 RNA Sequence

    Related
    ENSBTAT00000105216.1

  2. XR_009496034.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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